Literature DB >> 6576869

Experience with human lymphoblastoid interferon in acute myelogenous leukaemia (AML).

A Z Rohatiner, F R Balkwill, J S Malpas, T A Lister.   

Abstract

Fourteen patients with acute myelogenous leukaemia, who had either failed to enter remission or had relapsed following conventional chemotherapy, received human lymphoblastoid interferon (Hu IFN-alpha N) at a dose of 100 X 10(6) units/m2 daily by continuous IV infusion for 7 days. Complete remission was not achieved in any of 10 patients evaluable for response, although a transient decrease in the degree of bone marrow infiltration was observed in two patients.

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Year:  1983        PMID： 6576869     DOI： 10.1007/bf00257419

Source DB:  PubMed          Journal:  Cancer Chemother Pharmacol        ISSN： 0344-5704            Impact factor:   3.333


  11 in total

1.  Cytotoxic effects of interferon in vitro on granulocytic progenitor cells.

Authors:  P L Greenberg; S A Mosny
Journal:  Cancer Res       Date:  1977-06       Impact factor: 12.701

2.  High-dose cytosine arabinoside: clinical response to therapy in acute leukemia.

Authors:  A P Early; H D Preisler; D J Higby; M Brecher; G Browman; J A McBride
Journal:  Med Pediatr Oncol       Date:  1982

3.  Interferon and murine leukemia. I. Inhibitory effect of interferon preparations on development of friend leukemia in mice.

Authors:  I Gresser; J Coppey; E Falcoff; D Fontaine
Journal:  Proc Soc Exp Biol Med       Date:  1967-01

4.  A phase I study of human lymphoblastoid interferon administered by continuous intravenous infusion.

Authors:  A Z Rohatiner; F R Balkwill; D B Griffin; J S Malpas; T A Lister
Journal:  Cancer Chemother Pharmacol       Date:  1982       Impact factor: 3.333

5.  Interferon and murine leukemia. VII. Therapeutic effect of interferon preparations after diagnosis of lymphoma in AKR mice.

Authors:  I Gresser; C Maury; M Tovey
Journal:  Int J Cancer       Date:  1976-05-15       Impact factor: 7.396

6.  Inhibitory effects of human leukocyte and fibroblast interferons on normal and chronic myelogenous leukemic granulocytic progenitor cells.

Authors:  C K Williams; I Svet-Moldavskaya; J Vilcek; T Ohnuma; J F Holland
Journal:  Oncology       Date:  1981       Impact factor: 2.935

7.  Effect of interferon on colony formation in culture by blast cell progenitors in acute myeloblastic leukemia.

Authors:  R Taetle; R N Buick; E A McCulloch
Journal:  Blood       Date:  1980-09       Impact factor: 22.113

8.  Interferon and murine leukemia. V. Effect of interferon preparations on the evolution of Rauscher disease in mice.

Authors:  I Gresser; L Berman; G De Thé; D Brouty-Boyé; J Coppey; E Falcoff
Journal:  J Natl Cancer Inst       Date:  1968-08       Impact factor: 13.506

9.  Increased survival in mice inoculated with tumor cells and treated with interferon preparations.

Authors:  I Gresser; C Bourali; J P Lévy; D Fontaine-Brouty-Boyé; M T Thomas
Journal:  Proc Natl Acad Sci U S A       Date:  1969-05       Impact factor: 11.205

10.  Interferon and cell division. I. Inhibition of the multiplication of mouse leukemia L 1210 cells in vitro by interferon preparations.

Authors:  I Gresser; D Brouty-Boyé; M T Thomas; A Macieira-Coelho
Journal:  Proc Natl Acad Sci U S A       Date:  1970-08       Impact factor: 11.205
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  2 in total

1.  Growth inhibitory effects of interferon on blast cells from patients with acute myelogenous leukaemia.

Authors:  A Z Rohatiner
Journal:  Br J Cancer       Date:  1984-06       Impact factor: 7.640

Review 2.  The role of interferons in the treatment of malignant neoplasms.

Authors:  J R Murren; A C Buzaid
Journal:  Yale J Biol Med       Date:  1989 May-Jun
  2 in total

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