| Literature DB >> 6576853 |
R S Chaganti, S C Jhanwar, Z Arlin, B Koziner, A Ambati, M Andreeff, B D Clarkson.
Abstract
A patient with L3 leukemia is reported whose leukemic cells were characterized cytogenetically by a duplication of the long arm segment 1q25 leads to q42, trisomy for chromosome 7, t(8;22)(q24;q11), and two 14q+ chromosomes. Immunologic marker analysis revealed the leukemic cells to be of the non-T, non-B ("null") type. This observation, when considered in conjunction with a previous report of heterogeneity in cell lineages of L3 leukemias, raises the possibility of some lymphoid neoplasms arising in stem cells.Entities:
Mesh：
Year: 1983 PMID： 6576853 DOI： 10.1016/0165-4608(83)90110-3
Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN： 0165-4608