Literature DB >> 6573024

Inhibition of gastric acid secretion in the gastric brooding frog, Rheobatrachus silus.

M J Tyler, D J Shearman, R Franco, P O'Brien, R F Seamark, R Kelly.   

Abstract

The female gastric brooding frog Rheobatrachus silus broods its young in its stomach. A substance that inhibits gastric acid secretion in a toad stomach preparation in vitro appears to be secreted by the developing young. This substance has been identified as prostaglandin E2. Rheobatrachus silus may thus have developed a mechanism whereby prostaglandin secreted by the larvae inhibits acid secretion in the stomach of the female until the larvae have completed development and emerged as juvenile frogs by way of the female's mouth.

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Year:  1983        PMID: 6573024     DOI: 10.1126/science.6573024

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  3 in total

Review 1.  What is potent acid inhibition, and how can it be achieved?

Authors:  Xavier Calvet; Fernando Gomollón
Journal:  Drugs       Date:  2005       Impact factor: 9.546

2.  Prostanoids as friends, not foes: further evidence from the interference by cycloxygenase-inhibitory drugs when inducing tolerance to experimental arthritigens in rats.

Authors:  Michael W Whitehouse
Journal:  Inflammopharmacology       Date:  2005       Impact factor: 4.473

3.  Epitheliophagy: intrauterine cell nourishment in the viviparous alpine salamander, Salamandra atra (Laur.).

Authors:  G D Guex; P S Chen
Journal:  Experientia       Date:  1986-12-01
  3 in total

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