| Literature DB >> 6572280 |
C Paraskeva, C Roberts, P Biggs, P H Gallimore.
Abstract
Using resistance to the base analog 8-azaguanine as a genetic marker, we showed that adenovirus type 2, but not adenovirus type 12, is mutagenic at the hypoxanthine phosphoribosyltransferase locus of cloned diploid rat liver epithelial cells. Adenovirus type 2 increased the frequency of 8-azaguanine-resistant colonies by up to ninefold over the spontaneous frequency, depending on expression time and virus dose.Entities:
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Year: 1983 PMID: 6572280 PMCID: PMC255100
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103