Literature DB >> 6572280

Human adenovirus type 2 but not adenovirus type 12 is mutagenic at the hypoxanthine phosphoribosyltransferase locus of cloned rat liver epithelial cells.

C Paraskeva, C Roberts, P Biggs, P H Gallimore.   

Abstract

Using resistance to the base analog 8-azaguanine as a genetic marker, we showed that adenovirus type 2, but not adenovirus type 12, is mutagenic at the hypoxanthine phosphoribosyltransferase locus of cloned diploid rat liver epithelial cells. Adenovirus type 2 increased the frequency of 8-azaguanine-resistant colonies by up to ninefold over the spontaneous frequency, depending on expression time and virus dose.

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Year:  1983        PMID: 6572280      PMCID: PMC255100     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  23 in total

1.  Mutagenesis in cultured mammalian cells.

Authors:  N I Shapiro; N B Varshaver
Journal:  Methods Cell Biol       Date:  1975       Impact factor: 1.441

2.  The effect of calf serum on the toxicity of 8-azaguanine.

Authors:  A A van Zeeland; J W Simons
Journal:  Mutat Res       Date:  1975-01       Impact factor: 2.433

3.  Studies on in vitro transformation by DNA and DNA fragments of human adenoviruses and simian virus 40.

Authors:  F L Graham; P J Abrahams; C Mulder; H L Heijneker; S O Warnaar; F A De Vries; W Fiers; A J Van Der Eb
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1975

4.  Serum effect on the yield of chemically induced 8-azaguanine-resistant mutants in Chinese hamster cell cultures.

Authors:  D Wild
Journal:  Mutat Res       Date:  1974-11       Impact factor: 2.433

5.  An improved banding technique exemplified in the karyotype analysis of two strains of rat.

Authors:  P H Gallimore; C R Richardson
Journal:  Chromosoma       Date:  1973       Impact factor: 4.316

6.  Chromosomal aberrations and cloning efficiency in adenovirus type 12-infected hamster cells.

Authors:  H Zur Hausen
Journal:  J Virol       Date:  1968-09       Impact factor: 5.103

7.  Enzyme activities in extracts of 8-azaguanine-resistant mutants of cultured Chinese hamster cells induced by the carcinogen, 7-bromomethylbenz(a)anthracene.

Authors:  M E Duncan; P Brookes
Journal:  Mutat Res       Date:  1974-02       Impact factor: 2.433

Review 8.  Virus-induced chromosome abnormalities.

Authors:  W W Nichols
Journal:  Annu Rev Microbiol       Date:  1970       Impact factor: 15.500

9.  Mutagenic capacity of adenoviruses for mammalian cells.

Authors:  H F Stich; D S Yohn
Journal:  Nature       Date:  1967-12-30       Impact factor: 49.962

10.  Characterization of analog resistance and purine metabolism of adult rat-liver epithelial cell 8-azaguanine-resistant mutants.

Authors:  G M Williams; C Tong; J J Berman
Journal:  Mutat Res       Date:  1978-01       Impact factor: 2.433

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  3 in total

1.  "Hit-and-run" transformation by adenovirus oncogenes.

Authors:  M Nevels; B Täuber; T Spruss; H Wolf; T Dobner
Journal:  J Virol       Date:  2001-04       Impact factor: 5.103

2.  Plasmid mediated mutagenesis of a cellular gene in transfected eukaryotic cells.

Authors:  C R Brandt; F M Buonaguro; J K McDougall; D A Galloway
Journal:  Nucleic Acids Res       Date:  1987-01-26       Impact factor: 16.971

3.  Structure of the transforming region of human cytomegalovirus AD169.

Authors:  J A Nelson; B Fleckenstein; G Jahn; D A Galloway; J K McDougall
Journal:  J Virol       Date:  1984-01       Impact factor: 5.103

  3 in total

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