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Literature DB >> 6571788

Idiopathic refractory sideroachrestic anemia (IRSA) progressing to acute mixed lymphoblastic-myelomonoblastic leukemia. Case report and review of the literature.

R Hehlmann, B Zönnchen, E Thiel, B Walther.

Abstract

A longitudinal observation of a patient with idiopathic refractory sideroachrestic anemia (IRSA) progressing to acute mixed lymphoblastic-myelomonoblastic leukemia is reported. The leukemia was characterized by morphology, immunological cell markers, and dissociated clinical responsiveness to vincristine/prednisone and arabinosylcytosine/6-thioguanine. Attention is paid to the hematological changes prior to leukemia development. Acute leukemia was best heralded in this patient by a severe deterioration of dyserythropoiesis and by an increase of blasts in the marrow to more than 5%. The observed preleukemic features are compared to those described in the literature.

Entities: Chemical Disease Species

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Year: 1983 PMID： 6571788 DOI： 10.1007/bf00320001

Source DB: PubMed Journal: Blut ISSN： 0006-5242

32 in total

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Journal: Br J Haematol Date: 1965-01 Impact factor: 6.998

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Journal: Semin Hematol Date: 1976-04 Impact factor: 3.851

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Journal: Semin Hematol Date: 1974-01 Impact factor: 3.851

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Authors: G F Riedler; P W Straub
Journal: Blood Date: 1972-09 Impact factor: 22.113

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Authors: M I Saarni; J W Linman
Journal: Am J Med Date: 1973-07 Impact factor: 4.965

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Authors: R V Pierre
Journal: Semin Hematol Date: 1974-01 Impact factor: 3.851

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Journal: Blood Date: 1980-11 Impact factor: 22.113

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Authors: H P Koeffler; D W Golde
Journal: Ann Intern Med Date: 1980-08 Impact factor: 25.391

5 in total

Review 1. Transformation of myelodysplastic syndrome to acute lymphoblastic leukemia: a case report and review of the literature.

Authors: Norihide Sato; Tomonori Nakazato; Masahiro Kizaki; Yasuo Ikeda; Shinichiro Okamoto
Journal: Int J Hematol Date: 2004-02 Impact factor: 2.490

5. Myelodysplastic syndrome with myelofibrosis transformed to a precursor B-cell acute lymphoblastic leukemia: a case report with review of the literature.

Authors: Ayed A Algarni; Mojtaba Akhtari; Kai Fu
Journal: Case Rep Hematol Date: 2012-03-29