| Literature DB >> 656418 |
G Ehrenspeck, J Durham, W A Brodsky.
Abstract
Amiloride in the mucosal fluid (at concentrations of 5 . 10(-6) M to 10(-4) M) reversibly stimulates the HCO-3-dependent moiety of the short-circuiting current (Isc) in ouabain-treated turtle bladders bathed by Na-free Ringer solutions with or without Cl-. This effect is uniquely different from the known inhibitory effect of this agent on Na+ transport. Thus, any comprehensive hypothesis on the action of amiloride over a wide dosage-response range should take into account its effect on HCO-3 transport.Entities:
Mesh：
Substances：
Year: 1978 PMID： 656418 DOI： 10.1016/0005-2736(78)90057-3
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002