Literature DB >> 656294

Bronchodilator effect of delta1-tetrahydrocannabinol.

J P Hartley, S G Nogrady, A Seaton.   

Abstract

1 delta1-trans-tetrahydrocannabinol, (delta1-THC) produces bronchodilatation in asthmatic patients. 2 Administered in 62 microliter metered volumes containing 50--200 microgram by inhalation from an aerosol device to patients judged to be in a steady state, it increased peak expiratory flow rate (PEFR) and forced expiratory volume in 1 second (FEV1). 3 The rate of onset, magnitude, and duration of the bronchodilator effect was dose related.

Entities:  

Mesh：

Substances：

Year:  1978        PMID： 656294      PMCID： PMC1429361          DOI： 10.1111/j.1365-2125.1978.tb01667.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  8 in total

1.  Acute pulmonary physiologic effects of smoked marijuana and oral (Delta)9 -tetrahydrocannabinol in healthy young men.

Authors:  D P Tashkin; B J Shapiro; I M Frank
Journal:  N Engl J Med       Date:  1973-08-16       Impact factor: 91.245

2.  Acute effects of smoked marijuana and oral delta9-tetrahydrocannabinol on specific airway conductance in asthmatic subjects.

Authors:  D P Tashkin; B J Shapiro; I M Frank
Journal:  Am Rev Respir Dis       Date:  1974-04

3.  Single-dose effects of marihuana smoke. Bronchial dynamics and respiratory-center sensitivity in normal subjects.

Authors:  L Vachon; M X FitzGerald; N H Solliday; I A Gould; E A Gaensler
Journal:  N Engl J Med       Date:  1973-05-10       Impact factor: 91.245

4.  Respiratory manifestations of hashish smoking.

Authors:  R L Henderson; F S Tennant; R Guerry
Journal:  Arch Otolaryngol       Date:  1972-03

5.  Effects of smoked marijuana in experimentally induced asthma.

Authors:  D P Tashkin; B J Shapiro; Y E Lee; C E Harper
Journal:  Am Rev Respir Dis       Date:  1975-09

6.  A trial of oral delta-1-(trans)-tetrahydrocannabinol in reversible airways obstruction.

Authors:  B H Davies; S Radcliffe; A Seaton; J D Graham
Journal:  Thorax       Date:  1975-02       Impact factor: 9.139

7.  Bronchial effects of aerosolized delta 9-tetrahydrocannabinol in healthy and asthmatic subjects.

Authors:  D P Tashkin; S Reiss; B J Shapiro; B Calvarese; J L Olsen; J W Lodge
Journal:  Am Rev Respir Dis       Date:  1977-01

8.  Bronchodilator effect of delta1-tetrahydrocannabinol administered by aerosol of asthmatic patients.

Authors:  S J Williams; J P Hartley; J D Graham
Journal:  Thorax       Date:  1976-12       Impact factor: 9.139
  8 in total
  7 in total

Review 1.  Therapeutic potential of cannabinoids.

Authors:  D N Bateman; M D Rawlins
Journal:  Br Med J (Clin Res Ed)       Date:  1982-04-24

Review 2.  The endocannabinoid system as an emerging target of pharmacotherapy.

Authors:  Pál Pacher; Sándor Bátkai; George Kunos
Journal:  Pharmacol Rev       Date:  2006-09       Impact factor: 25.468

3.  Characterization of the effects of cannabinoids on guinea-pig tracheal smooth muscle tone: role in the modulation of acetylcholine release from parasympathetic nerves.

Authors:  L Spicuzza; E B Haddad; M Birrell; A Ling; D Clarke; P Venkatesan; P J Barnes; M G Belvisi
Journal:  Br J Pharmacol       Date:  2000-08       Impact factor: 8.739

Review 4.  Cannabinoids as novel anti-inflammatory drugs.

Authors:  Prakash Nagarkatti; Rupal Pandey; Sadiye Amcaoglu Rieder; Venkatesh L Hegde; Mitzi Nagarkatti
Journal:  Future Med Chem       Date:  2009-10       Impact factor: 3.808

Review 5.  Pharmacokinetics and pharmacodynamics of cannabinoids.

Authors:  Franjo Grotenhermen
Journal:  Clin Pharmacokinet       Date:  2003       Impact factor: 6.447

Review 6.  Cannabinoids in health and disease.

Authors:  Natalya M Kogan; Raphael Mechoulam
Journal:  Dialogues Clin Neurosci       Date:  2007       Impact factor: 5.986

Review 7.  Endocannabinoid System in the Airways.

Authors:  Turgut Emrah Bozkurt
Journal:  Molecules       Date:  2019-12-17       Impact factor: 4.411
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.