Literature DB >> 656271

The effects of intravenous isoxsuprine on blood viscosity in patients with occlusive peripheral arterial disease.

T Di Perri, S Forconi, D Agnusdei, M Guerrini, F Laghi Pasini.   

Abstract

1 Blood viscosity is thought to be a major factor in disorders of the peripheral circulation. 2 Ten patients with obliterative arterial disease received an infusion of isoxsuprine of 20 micrograms kg-1 for 30 min. The infusion was followed by a highly significant and prolonged fall in blood, plasma and serum viscosity, in haematocrit and in plasma fibrinogen concentration. Blood lipid levels were also studied: total lipids and total cholesterol did not alter; triglyceride level was significantly lowered at the end of, and after, drug infusion. 3 There was no change in blood, plasma or serum viscosity in the four patients receiving a control infusion 2 days before the infusion of isoxsuprine. 4 The relationships between lowered viscosity and increasing peripheral tissue perfusion are discussed.

Entities:  

Mesh:

Substances:

Year:  1978        PMID: 656271      PMCID: PMC1429281          DOI: 10.1111/j.1365-2125.1978.tb01633.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN: 0306-5251            Impact factor:   4.335


  19 in total

1.  SOME OBSERVATIONS ON THE VISCOSITY OF PATHOLOGICAL HUMAN BLOOD PLASMA.

Authors:  L DINTENFASS
Journal:  Thromb Diath Haemorrh       Date:  1965-06-15

2.  A simple method for the determination of serum cholesterol.

Authors:  D WATSON
Journal:  Clin Chim Acta       Date:  1960-09       Impact factor: 3.786

3.  Blood viscosity, serum hexosamine and diabetic retinopathy.

Authors:  D G COGAN; L MEROLA; P R LAIBSON
Journal:  Diabetes       Date:  1961 Sep-Oct       Impact factor: 9.461

4.  Use of antimalarial drugs as "desludging" agents in vascular disease processes.

Authors:  B P MADOW
Journal:  J Am Med Assoc       Date:  1960-04-09

5.  Bicarbonate therapy during embolectomy. Prevention of acidosis shock and acidosis arrest.

Authors:  J S Stewart; J W Mostert; D D Hilton; D McGrath
Journal:  Lancet       Date:  1965-12-25       Impact factor: 79.321

6.  Reduction in blood viscosity at low rates of shear by surface active substances: a new hemorheologic phenomenon.

Authors:  A M Ehrly
Journal:  Biorheology       Date:  1968-09       Impact factor: 1.875

7.  Blood-viscosity in diabetic patients.

Authors:  F Skovborg; A V Nielsen; J Schlichtkrull; J Ditzel
Journal:  Lancet       Date:  1966-01-15       Impact factor: 79.321

8.  Viscosity of blood in normal subjects and in patients suffering from coronary occlusion and arterial thrombosis. An in vitro study in the absence of anticoagulants, by means of a rotational cone-in-cone trolley viscometer.

Authors:  L Dintenfass; D G Julian; G E Miller
Journal:  Am Heart J       Date:  1966-05       Impact factor: 4.749

9.  [A new determination of the neutral fats in blood serum and tissue. II. Reliability of the method, other neutral fat determinations, normal values for triglycerides and glycerin in human blood].

Authors:  M Eggstein
Journal:  Klin Wochenschr       Date:  1966-03-01

10.  Disturbance of serum viscosity in diabetes mellitus.

Authors:  D E McMillan
Journal:  J Clin Invest       Date:  1974-04       Impact factor: 14.808

View more
  1 in total

Review 1.  Blood rheology.

Authors:  J Stuart; M W Kenny
Journal:  J Clin Pathol       Date:  1980-05       Impact factor: 3.411

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.