| Literature DB >> 6562018 |
F Markwardt, J Stürzebecher, H Müller.
Abstract
Glandular kallikrein can be temporarily acylated at the active centre by 4-amidinophenyl benzoates. The time course of reactivation depends on the nature of the acyl group introduced. Benzoyl kallikrein was used as a delivery system for kallikrein in vivo. In rabbits, bolus injection of the acylated enzyme caused a long-lasting drop in blood pressure due to sustained kinin liberation.Entities:
Mesh:
Substances:
Year: 1984 PMID: 6562018 DOI: 10.1007/bf01952559
Source DB: PubMed Journal: Experientia ISSN: 0014-4754