Literature DB >> 656104

Anti-proliferative properties of DL-alpha-difluoromethyl ornithine in cultured cells. A consequence of the irreversible inhibition of ornithine decarboxylase.

P S Mamont, M C Duchesne, J Grove, P Bey.   

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Year:  1978        PMID： 656104     DOI： 10.1016/0006-291x(78)91630-3

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


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  96 in total

1.  Seminal polyamines as agents of cervical carcinoma: production of aneuploidy in squamous epithelium.

Authors:  S Fletcher; W A Neill; M Norval
Journal:  J Clin Pathol       Date:  1991-05       Impact factor: 3.411

2.  Panagrellus redivivus ornithine decarboxylase: structure of the gene, expression in Escherichia coli and characterization of the recombinant protein.

Authors:  G Niemann; H von Besser; R D Walter
Journal:  Biochem J       Date:  1996-07-01       Impact factor: 3.857

3.  Polyamines and HeLa-cell DNA replication.

Authors:  C J Gallo; R A Koza; E J Herbst
Journal:  Biochem J       Date:  1986-08-15       Impact factor: 3.857

Review 4.  Recent advances in the development of polyamine analogues as antitumor agents.

Authors:  Robert A Casero; Patrick M Woster
Journal:  J Med Chem       Date:  2009-08-13       Impact factor: 7.446

5.  Phase I study of combined alpha interferon, alpha difluoromethylornithine (DFMO), and doxorubicin in advanced malignancy.

Authors:  V Ganju; J H Edmonson; J C Buckner
Journal:  Invest New Drugs       Date:  1994       Impact factor: 3.850

6.  Retinoids increase transglutaminase activity and inhibit ornithine decarboxylase activity in Chinese hamster ovary cells and in melanoma cells stimulated to differentiate.

Authors:  K F Scott; F L Meyskens; D H Russell
Journal:  Proc Natl Acad Sci U S A       Date:  1982-07       Impact factor: 11.205

Review 7.  Cancer pharmacoprevention: Targeting polyamine metabolism to manage risk factors for colon cancer.

Authors:  Eugene W Gerner; Elizabeth Bruckheimer; Alfred Cohen
Journal:  J Biol Chem       Date:  2018-10-24       Impact factor: 5.157

8.  D,L-alpha-difluoromethylornithine inhibits human cytomegalovirus replication.

Authors:  W Gibson; R van Breemen; A Fields; R LaFemina; A Irmiere
Journal:  J Virol       Date:  1984-04       Impact factor: 5.103

9.  The role of polyamine depletion and accumulation of decarboxylated S-adenosylmethionine in the inhibition of growth of SV-3T3 cells treated with alpha-difluoromethylornithine.

Authors:  A E Pegg
Journal:  Biochem J       Date:  1984-11-15       Impact factor: 3.857

10.  Reversal of the growth inhibitory effect of alpha-difluoromethylornithine by putrescine but not by other divalent cations.

Authors:  S M Oredsson; S Anehus; O Heby
Journal:  Mol Cell Biochem       Date:  1984-09       Impact factor: 3.396
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