Literature DB >> 6548963

Immunostimulating hexapeptide from human casein: amino acid sequence, synthesis and biological properties.

F Parker, D Migliore-Samour, F Floc'h, A Zerial, G H Werner, J Jollès, M Casaretto, H Zahn, P Jollès.   

Abstract

A hexapeptide obtained from human casein by enzymatic digestion has been purified, sequenced and synthesized; its structure is: Val-Glu-Pro-Ile-Pro-Tyr. In vitro this hexapeptide stimulates the phagocytosis of opsonized sheep red blood cells by murine peritoneal macrophages. Administered intravenously to adult mice, it enhances the resistance to infection with Klebsiella pneumoniae.

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Year:  1984        PMID: 6548963     DOI: 10.1111/j.1432-1033.1984.tb08609.x

Source DB:  PubMed          Journal:  Eur J Biochem        ISSN: 0014-2956


  12 in total

Review 1.  Biologically active peptides in milk proteins.

Authors:  H Meisel; H Frister; E Schlimme
Journal:  Z Ernahrungswiss       Date:  1989-12

Review 2.  Immunomodulating peptides.

Authors:  G H Werner; F Floc'h; D Migliore-Samour; P Jollès
Journal:  Experientia       Date:  1986-05-15

Review 3.  Casein, a prohormone with an immunomodulating role for the newborn?

Authors:  D Migliore-Samour; P Jollès
Journal:  Experientia       Date:  1988-03-15

Review 4.  Caseins of various origins and biologically active casein peptides and oligosaccharides: structural and physiological aspects.

Authors:  A M Fiat; P Jollès
Journal:  Mol Cell Biochem       Date:  1989-05-04       Impact factor: 3.396

5.  Extraction, Isolation and Identification of Low Molecular Weight Peptides in Human Milk.

Authors:  Hailong Xiao; He Jiang; Haiyun Tu; Yanbo Jia; Hongqing Wang; Xin Lü; Ruosi Fang; Gongnian Xiao
Journal:  Foods       Date:  2022-06-22

6.  2008 Landis Award lecture. Inflammation and the autodigestion hypothesis.

Authors:  Geert W Schmid-Schönbein
Journal:  Microcirculation       Date:  2009-05       Impact factor: 2.628

7.  Beta-casomorphin (BCM) and human colonic lamina propria lymphocyte proliferation.

Authors:  Y Elitsur; G D Luk
Journal:  Clin Exp Immunol       Date:  1991-09       Impact factor: 4.330

8.  Milk Peptides Survive In Vivo Gastrointestinal Digestion and Are Excreted in the Stool of Infants.

Authors:  Robert L Beverly; Robert K Huston; Andi M Markell; Elizabeth A McCulley; Rachel L Martin; David C Dallas
Journal:  J Nutr       Date:  2020-04-01       Impact factor: 4.798

9.  Human beta casein fragment (54-59) modulates M. bovis BCG survival and basic transcription factor 3 (BTF3) expression in THP-1 cell line.

Authors:  Dharamsheela Thakur; Reshu Saxena; Vandana Singh; Wahajul Haq; S B Katti; Bhupendra Narain Singh; Raj Kamal Tripathi
Journal:  PLoS One       Date:  2012-09-28       Impact factor: 3.240

10.  Effects of 'casoparan', a peptide isolated from casein hydrolysates with mastoparan-like properties.

Authors:  Ivo Lebrun; Valéria Cavallaro; Luiz Juliano; Maria A Juliano; Maria C C de Sousa e Silva
Journal:  Mediators Inflamm       Date:  2004-08       Impact factor: 4.711

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