Literature DB >> 6548737

Studies on new antifungal antibiotics, guanidylfungins A and B. II. Structure elucidation and biosynthesis.

K Takesako, T Beppu.   

Abstract

The structures of guanidylfungins A and B were elucidated from the physico-chemical properties of these compounds and the structures of the degradation products by ozonolysis and periodate oxidation. The guanidylfungins consist of a 36-membered polyhydroxyl lactone ring, a guanidine and a monoester of malonic acid. The labelling experiments with sodium [1-13C]acetate and sodium [1-13C]propionate revealed that twelve units of acetate and nine of propionate were incorporated into the molecule of guanidylfungin A.

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Year:  1984        PMID： 6548737     DOI： 10.7164/antibiotics.37.1170

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  4 in total

Review 1.  Guanidine-Containing Polyhydroxyl Macrolides: Chemistry, Biology, and Structure-Activity Relationship.

Authors:  Xiaoyuan Song; Ganjun Yuan; Peibo Li; Sheng Cao
Journal:  Molecules       Date:  2019-10-30       Impact factor: 4.411

Review 2.  The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

Authors:  James B McAlpine; Shao-Nong Chen; Andrei Kutateladze; John B MacMillan; Giovanni Appendino; Andersson Barison; Mehdi A Beniddir; Maique W Biavatti; Stefan Bluml; Asmaa Boufridi; Mark S Butler; Robert J Capon; Young H Choi; David Coppage; Phillip Crews; Michael T Crimmins; Marie Csete; Pradeep Dewapriya; Joseph M Egan; Mary J Garson; Grégory Genta-Jouve; William H Gerwick; Harald Gross; Mary Kay Harper; Precilia Hermanto; James M Hook; Luke Hunter; Damien Jeannerat; Nai-Yun Ji; Tyler A Johnson; David G I Kingston; Hiroyuki Koshino; Hsiau-Wei Lee; Guy Lewin; Jie Li; Roger G Linington; Miaomiao Liu; Kerry L McPhail; Tadeusz F Molinski; Bradley S Moore; Joo-Won Nam; Ram P Neupane; Matthias Niemitz; Jean-Marc Nuzillard; Nicholas H Oberlies; Fernanda M M Ocampos; Guohui Pan; Ronald J Quinn; D Sai Reddy; Jean-Hugues Renault; José Rivera-Chávez; Wolfgang Robien; Carla M Saunders; Thomas J Schmidt; Christoph Seger; Ben Shen; Christoph Steinbeck; Hermann Stuppner; Sonja Sturm; Orazio Taglialatela-Scafati; Dean J Tantillo; Robert Verpoorte; Bin-Gui Wang; Craig M Williams; Philip G Williams; Julien Wist; Jian-Min Yue; Chen Zhang; Zhengren Xu; Charlotte Simmler; David C Lankin; Jonathan Bisson; Guido F Pauli
Journal:  Nat Prod Rep       Date:  2018-07-13       Impact factor: 13.423

3.  Metabolomic profiling and genomic study of a marine sponge-associated Streptomyces sp.

Authors:  Christina Viegelmann; Lekha Menon Margassery; Jonathan Kennedy; Tong Zhang; Ciarán O'Brien; Fergal O'Gara; John P Morrissey; Alan D W Dobson; RuAngelie Edrada-Ebel
Journal:  Mar Drugs       Date:  2014-06-02       Impact factor: 5.118

4.  Antifungal Substances from Streptomyces sp. A3265 Antagonistic to Plant Pathogenic Fungi.

Authors:  Nguyen Van Minh; E-Eum Woo; Ji-Yul Kim; Dae-Won Kim; Byung Soon Hwang; Yoon-Ju Lee; In-Kyoung Lee; Bong-Sik Yun
Journal:  Mycobiology       Date:  2015-09-30       Impact factor: 1.858
  4 in total

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