Literature DB >> 6548620

Urinary excretion of the N-acetyl cysteine conjugate of cis-1,3-dichloropropene by exposed individuals.

J D Osterloh, B S Cohen, W Popendorf, S M Pond.   

Abstract

A gas chromatographic-mass spectrometric assay was developed to identify and measure the N-acetyl cysteine conjugate of cis-1,3-dichloropropene. The assay was used to show that individuals exposed to 1,3-dichloropropene vapor during field applications excrete this conjugate in their urine. The recoveries of the conjugate were correlated with the product of airborne concentrations and the duration of exposure (r = 0.83).

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Year:  1984        PMID： 6548620     DOI： 10.1080/00039896.1984.10545848

Source DB:  PubMed          Journal:  Arch Environ Health        ISSN： 0003-9896


  3 in total

1.  Genetic deficiency of human class mu glutathione S-transferase isoenzymes in relation to the urinary excretion of the mercapturic acids of Z- and E-1,3-dichloropropene.

Authors:  R M Vos; R T van Welie; W H Peters; C T Evelo; J J Boogaards; N P Vermeulen; P J van Bladeren
Journal:  Arch Toxicol       Date:  1991       Impact factor: 5.153

2.  Identification and quantitative determination of mercapturic acids formed from Z- and E-1,3-dichloropropene by the rat, using gas chromatography with three different detection techniques.

Authors:  W Onkenhout; P P Mulder; P J Boogaard; W Buijs; N P Vermeulen
Journal:  Arch Toxicol       Date:  1986-12       Impact factor: 5.153

3.  Inhalation exposure to 1,3-dichloropropene in the Dutch flower-bulb culture. Part II. Biological monitoring by measurement of urinary excretion of two mercapturic acid metabolites.

Authors:  R T van Welie; P van Duyn; D H Brouwer; J J van Hemmen; E J Brouwer; N P Vermeulen
Journal:  Arch Environ Contam Toxicol       Date:  1991-01       Impact factor: 2.804
  3 in total

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