Literature DB >> 6547655

ELSMOS--an extended least squares modelling system in FORTRAN IV for mini- or micro-computer implementation.

R J Francis.   

Abstract

A new program ELSMOS has been developed for curve fitting of pharmacokinetic and pharmacodynamic data. The form is sufficiently general, with user-defined model in a separate FORTRAN subroutine, to permit application in many other areas. The principal features are the use of a user-defined error model for statistically rigorous automatic weighting of data, and the containment of program size to a level that enables mini- or micro-computer implementation.

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Year:  1984        PMID： 6547655     DOI： 10.1016/0010-468x(84)90022-9

Source DB:  PubMed          Journal:  Comput Programs Biomed        ISSN： 0010-468X


  20 in total

1.  The influence of Org 10172, a low molecular weight heparinoid, on antipyrine metabolism and the effect of enzyme induction on the response to Org 10172.

Authors:  A De Boer; J C Stiekema; M Danhof; D D Breimer
Journal:  Br J Clin Pharmacol       Date:  1991-07       Impact factor: 4.335

2.  The effect of perindopril and hydrochlorothiazide alone and in combination on blood pressure and on the renin-angiotensin system in hypertensive subjects.

Authors:  C L Brown; C I Backhouse; J C Grippat; J P Santoni
Journal:  Eur J Clin Pharmacol       Date:  1990       Impact factor: 2.953

Review 3.  The use of kinetic-dynamic interactions in the evaluation of drugs.

Authors:  D B Campbell
Journal:  Psychopharmacology (Berl)       Date:  1990       Impact factor: 4.530

4.  Oral absorption profile of nitrendipine in healthy subjects: a kinetic and dynamic study.

Authors:  P A Soons; A G de Boer; P van Brummelen; D D Breimer
Journal:  Br J Clin Pharmacol       Date:  1989-02       Impact factor: 4.335

5.  Pharmacokinetics of tenoxicam after oral administration in healthy human subjects of various single doses.

Authors:  R J Francis; J G Allen; D Looi; J S Dixon; H A Bird; V Wright
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1987 Jan-Mar       Impact factor: 2.441

6.  The pharmacokinetics of intravenous and oral levodopa in patients with Parkinson's disease who exhibit on-off fluctuations.

Authors:  R J Hardie; S L Malcolm; A J Lees; G M Stern; J G Allen
Journal:  Br J Clin Pharmacol       Date:  1986-10       Impact factor: 4.335

7.  Ro 31-1118, a new cardioselective beta-adrenoceptor antagonist. Pharmacokinetics and effects on heart rate and blood pressure in mild hypertensives.

Authors:  M Jamieson; J C Petrie; J Webster; A Miller; R I Harris; R J Francis
Journal:  Eur J Clin Pharmacol       Date:  1985       Impact factor: 2.953

8.  Theophylline pharmacokinetics following single and repeated administration of slow-release capsules.

Authors:  J Torrent; I Izquierdo; M J Barbanoj; R Obach; M Nomen; F Jane
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1988 Oct-Dec       Impact factor: 2.441

9.  Pharmacokinetics of nicomorphine and its metabolites in man after epidural administration.

Authors:  P M Koopman-Kimenai; T B Vree; M A Hasenbos; E W Weber; C P Verweij-Van Wissen; L H Booij
Journal:  Pharm Weekbl Sci       Date:  1991-06-21

10.  Pharmacokinetic-pharmacodynamic modelling of the anticonvulsant effect of oxazepam in individual rats.

Authors:  J Dingemanse; R A Voskuyl; M W Langemeijer; I Postel-Westra; D D Breimer; H Meinardi; M Danhof
Journal:  Br J Pharmacol       Date:  1990-01       Impact factor: 8.739
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