Literature DB >> 6547584

Isolation and characterization of a novel disialoganglioside from bovine adrenal medulla.

T Ariga, M Sekine, R K Yu, T Miyatake.   

Abstract

A novel GDlb ganglioside which contains only N-glycolylneuraminic acid was isolated from bovine adrenal medulla by DEAE-Sephadex A-25 and Iatrobeads column chromatography. The concentration of this ganglioside was 0.9 nmol lipid-bound sialic acid per gram fresh tissue, which accounted for 2.7% of the disialoganglioside fraction. The structure was elucidated by sugar analysis, neuraminidase digestion, and permethylation studies. The complete structure of this ganglioside was identified as GDlb (NeuGc)2 or II3 (NeuGc)2-GgOse4Cer.

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Year:  1984        PMID: 6547584     DOI: 10.1016/0003-9861(84)90546-0

Source DB:  PubMed          Journal:  Arch Biochem Biophys        ISSN: 0003-9861            Impact factor:   4.013


  1 in total

1.  Anti-Chol-1 antigen, GQ1bα, antibodies are associated with Alzheimer's disease.

Authors:  Toshio Ariga; Masaru Kubota; Makoto Nakane; Kenji Oguro; Robert K Yu; Susumu Ando
Journal:  PLoS One       Date:  2013-05-23       Impact factor: 3.240

  1 in total

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