| Literature DB >> 6547475 |
J M Garvey, M Rossor, L L Iversen.
Abstract
Pirenzepine, a compound with selective antimuscarinic activity, was used to distinguish muscarinic acetylcholine receptor subtypes in normal human brain. Hill coefficients and IC50 values derived from the inhibition of specific [3H]L-quinuclidinyl benzilate receptor binding suggest the presence of two muscarinic binding sites, differing both in affinity for pirenzepine and in tissue distribution.Entities:
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Year: 1984 PMID： 6547475 DOI： 10.1111/j.1471-4159.1984.tb00900.x
Source DB: PubMed Journal: J Neurochem ISSN： 0022-3042 Impact factor: 5.372