Literature DB >> 6547134

Studies on macrocyclic lactone antibiotics. VII. Structure of a phytotoxin "rhizoxin" produced by Rhizopus chinensis.

S Iwasaki, H Kobayashi, J Furukawa, M Namikoshi, S Okuda, Z Sato, I Matsuda, T Noda.   

Abstract

A new 16-membered macrolide designated as rhizoxin was isolated as a toxin produced by Rhizopus chinensis, the causal agent of rice seedling blight . The skeletal structure was determined by detailed NMR spectroscopic investigation of this compound and of its derivatives. Rhizoxin induced at a concentration of 10 ng/ml abnormal swelling of rice seedling roots, which is one of the characteristic symptoms of this disease. This compound also exhibited potent antifungal activity but little effect against bacteria.

Entities:  

Mesh：

Substances：

Year:  1984        PMID： 6547134     DOI： 10.7164/antibiotics.37.354

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  23 in total

Review 1.  Antimicrotubular drugs binding to vinca domain of tubulin.

Authors:  Suvroma Gupta; Bhabatarak Bhattacharyya
Journal:  Mol Cell Biochem       Date:  2003-11       Impact factor: 3.396

2.  Global distribution and evolution of a toxinogenic Burkholderia-Rhizopus symbiosis.

Authors:  Gerald Lackner; Nadine Möbius; Kirstin Scherlach; Laila P Partida-Martinez; Robert Winkler; Imke Schmitt; Christian Hertweck
Journal:  Appl Environ Microbiol       Date:  2009-03-13       Impact factor: 4.792

3.  In vitro and in vivo modulation by rhizoxin of non-P-glycoprotein-mediated vindesine resistance.

Authors:  H Arioka; K Nishio; Y Heike; S Abe; N Saijo
Journal:  J Cancer Res Clin Oncol       Date:  1997       Impact factor: 4.553

4.  Burkholderia as a Source of Natural Products.

Authors:  Sylvia Kunakom; Alessandra S Eustáquio
Journal:  J Nat Prod       Date:  2019-07-11       Impact factor: 4.050

Review 5.  Toward a Cancer Drug of Fungal Origin.

Authors:  Alexander Kornienko; Antonio Evidente; Maurizio Vurro; Véronique Mathieu; Alessio Cimmino; Marco Evidente; Willem A L van Otterlo; Ramesh Dasari; Florence Lefranc; Robert Kiss
Journal:  Med Res Rev       Date:  2015-04-08       Impact factor: 12.944

6.  Tumor selective effect of RS-1541 (palmitoyl-rhizoxin) in M5076 sarcoma and host tissues in vivo.

Authors:  T Tokui; N Maeda; C Kuroiwa; K Sasagawa; T Inoue; K Kawai; T Ikeda; T Komai
Journal:  Pharm Res       Date:  1995-03       Impact factor: 4.200

7.  Isolation and identification of rhizoxin analogs from Pseudomonas fluorescens Pf-5 by using a genomic mining strategy.

Authors:  Joyce E Loper; Marcella D Henkels; Brenda T Shaffer; Frederick A Valeriote; Harald Gross
Journal:  Appl Environ Microbiol       Date:  2008-03-14       Impact factor: 4.792

8.  Bacterial-Like Nonribosomal Peptide Synthetases Produce Cyclopeptides in the Zygomycetous Fungus Mortierella alpina.

Authors:  Jacob M Wurlitzer; Aleksa Stanišić; Ina Wasmuth; Sandra Jungmann; Dagmar Fischer; Hajo Kries; Markus Gressler
Journal:  Appl Environ Microbiol       Date:  2021-01-15       Impact factor: 4.792

9.  Delivery and cytotoxicity of RS-1541 in St-4 human gastric cancer cells in vitro by the low-density-lipoprotein pathway.

Authors:  T Tokui; T Takatori; N Shinozaki; M Ishigami; A Shiraishi; T Ikeda; T Tsuruo
Journal:  Cancer Chemother Pharmacol       Date:  1995       Impact factor: 3.333

10.  Intracellular activation and cytotoxic action of RS-1541 against cultured human tumor cells.

Authors:  T Takatori; T Koizumi; T Tokui; Y Mitsuhashi; A Shiraishi; T Tsuruo
Journal:  Cancer Chemother Pharmacol       Date:  1995       Impact factor: 3.333
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.