Literature DB >> 6547114

A free derivative program for non-linear regression analysis of enzyme kinetics to be used on small computers.

E I Canela.   

Abstract

A non-linear regression program, written in BASIC, is described. The program uses the Marquardt 's algorithm as modified by Reich et al. (Eur. J. Biochem., 26 (1972) pp. 368-379). The user only supplies the expression to fit, since the program uses numerical differentiation. It is possible to fit models of 1 substrate, 2 substrates, 1 substrate and 1 inhibitor, and 2 substrates and 1 inhibitor. Likewise, several weighting patterns, as well as a simple or robust regression, can be selected.

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Year:  1984        PMID: 6547114     DOI: 10.1016/0020-7101(84)90024-2

Source DB:  PubMed          Journal:  Int J Biomed Comput        ISSN: 0020-7101


  13 in total

1.  Characterization of adenosine receptors in brush-border membranes from pig kidney.

Authors:  J Blanco; E I Canela; J Mallol; C Lluís; R Franco
Journal:  Br J Pharmacol       Date:  1992-11       Impact factor: 8.739

2.  Fitting integrated enzyme rate equations to progress curves with the use of a weighting matrix.

Authors:  R Franco; J M Aran; E I Canela
Journal:  Biochem J       Date:  1991-03-01       Impact factor: 3.857

3.  Generation process of cytosolic aspartate aminotransferase molecular forms by several treatments.

Authors:  S Imperial; C Quiroga; M Busquets; A Cortés; J Bozal
Journal:  J Protein Chem       Date:  1988-04

4.  A computer program for enzyme kinetics that combines model discrimination, parameter refinement and sequential experimental design.

Authors:  R Franco; M T Gavaldà; E I Canela
Journal:  Biochem J       Date:  1986-09-15       Impact factor: 3.857

5.  Enzyme kinetic studies from progress curves.

Authors:  E I Canela; R Franco
Journal:  Biochem J       Date:  1986-01-15       Impact factor: 3.857

6.  The role of a low beta 1-adrenoceptor selectivity of [3H]CGP-12177 for resolving subtype-selectivity of competitive ligands.

Authors:  C Nanoff; M Freissmuth; W Schütz
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1987-11       Impact factor: 3.000

7.  Kinetic studies of chicken and turkey liver mitochondrial aspartate aminotransferase.

Authors:  M Cascante; A Cortés
Journal:  Biochem J       Date:  1988-03-15       Impact factor: 3.857

8.  Kinetics of the 5'-nucleotidase and the adenosine deaminase in subcellular fractions of rat brain.

Authors:  J J Centelles; R Franco; E I Canela; J Bozal
Journal:  Neurochem Res       Date:  1986-04       Impact factor: 3.996

9.  The distribution of A1 adenosine receptor and 5'-nucleotidase in pig brain cortex subcellular fractions.

Authors:  V Casadó; C Lluis; E Canela; R Franco; J Mallol
Journal:  Neurochem Res       Date:  1992-02       Impact factor: 3.996

10.  Kinetic mechanism of chicken liver xanthine dehydrogenase.

Authors:  P Bruguera; A Lopez-Cabrera; E I Canela
Journal:  Biochem J       Date:  1988-01-01       Impact factor: 3.857

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