| Literature DB >> 6546606 |
S M Hedrick, E A Nielsen, J Kavaler, D I Cohen, M M Davis.
Abstract
Comparison of the sequence of a cloned T cell-specific cDNA with those of cross-reacting cloned cDNAs isolated from a thymocyte library indicates the presence of variable, constant and joining regions remarkably similar in size and sequence to those encoding immunoglobulin proteins. Together with the evidence for somatic gene rearrangements reported in the accompanying paper, this strongly suggests that the TM86 cDNA clone encodes one chain of the T-cell receptor for antigen.Mesh:
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Year: 1984 PMID: 6546606 DOI: 10.1038/308153a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962