Congenital familial external ophthalmoplegia with co-contraction.

A family fitting the criterion for congenital familial fibrosis has electromyographic and clinical evidence of co-contraction. Forced ductions were negative in one patient. Muscle fibrosis in this family is thought to be secondary to the innervational anomaly akin to Duane's syndrome rather than a primary myogenic etiology. The evidence of a brainstem etiology makes classification as an ophthalmoplegia seem more appropriate.