Literature DB >> 6543689

The demonstration of nonlinear development of experimental lung tumor metastases.

A Raz.   

Abstract

The kinetics of tumor colony formation in the lungs of mice following intravenous inoculation of high and low metastatic cell variants was determined. We have utilized two different tumor systems, the B16 melanoma, and UV-2237 fibrosarcoma; in both tumors the highly metastatic cell variants developed lung metastases in a nonlinear fashion following i.v. inoculation. The possibility that highly metastatic cell variants differ from their low metastatic counterparts not only in their lung colonizing potential, but also in their capability to produce satellite colonies, is discussed.

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Year:  1984        PMID: 6543689     DOI: 10.1007/bf00132303

Source DB:  PubMed          Journal:  Clin Exp Metastasis        ISSN: 0262-0898            Impact factor:   5.150


  20 in total

1.  Electron microscopic observations on formation of pulmonary metastases.

Authors:  W F Sindelar; T S Tralka; A S Ketcham
Journal:  J Surg Res       Date:  1975-02       Impact factor: 2.192

2.  Experiments on the Spread of Neoplastic Cells Through the Respiratory Passages.

Authors:  J Furth
Journal:  Am J Pathol       Date:  1946-11       Impact factor: 4.307

3.  Method for quantitating tumor cell removal and tumor cell-invasive capacity in experimental metastases.

Authors:  L A Liotta; C DeLisi
Journal:  Cancer Res       Date:  1977-11       Impact factor: 12.701

Review 4.  Cancer metastasis. Organ colonization and the cell-surface properties of malignant cells.

Authors:  G L Nicolson
Journal:  Biochim Biophys Acta       Date:  1982-12-21

5.  Characterization in vivo and in vitro of tumor cells selected for resistance to syngeneic lymphocyte-mediated cytotoxicity.

Authors:  I J Fidler; D M Gersten; M B Budmen
Journal:  Cancer Res       Date:  1976-09       Impact factor: 12.701

6.  Arrest and retention of circulating cancer cells in the lungs of animals with defined metastatic status.

Authors:  L Weiss; P M Ward
Journal:  Cancer Res       Date:  1982-05       Impact factor: 12.701

7.  Arrest and metastasis of blood-borne tumor cells are modified by fusion of plasma membrane vesicles from highly metastatic cells.

Authors:  G Poste; G L Nicolson
Journal:  Proc Natl Acad Sci U S A       Date:  1980-01       Impact factor: 11.205

8.  In vivo isolation of a metastatic tumor cell variant involving selective and nonadaptive processes.

Authors:  A Raz; N Hanna; I J Fidler
Journal:  J Natl Cancer Inst       Date:  1981-01       Impact factor: 13.506

9.  Host treatments affecting artificial pulmonary metastases: interpretation of loss of radioactively labelled cells from lungs.

Authors:  J M Brown; E T Parker
Journal:  Br J Cancer       Date:  1979-11       Impact factor: 7.640

10.  Murine melanoma: a model for intracranial metastasis.

Authors:  A Raz; I R Hart
Journal:  Br J Cancer       Date:  1980-08       Impact factor: 7.640

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  2 in total

1.  Multiple phenotypic divergence of mammary adenocarcinoma cell clones. I. In vitro and in vivo properties.

Authors:  D R Welch; D B Krizman; G L Nicolson
Journal:  Clin Exp Metastasis       Date:  1984 Oct-Dec       Impact factor: 5.150

2.  Dynamic heterogeneity: isolation of murine tumor cell populations enriched for metastatic variants and quantification of the unstable expression of the phenotype.

Authors:  S D Young; R P Hill
Journal:  Clin Exp Metastasis       Date:  1986 Jul-Sep       Impact factor: 5.150

  2 in total

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