Literature DB >> 6542229

Apomorphine-induced stereotypy: function of age and rearing environment.

B Chitkara, M J Durcan, I C Campbell.   

Abstract

Rats of different age groups ("young" vs. "old"), reared in isolation and social groups were tested for differences in apomorphine-induced stereotypy. Sensitivity to apomorphine (2 mg/kg SC) was found to be a function of an interaction between rearing environment and age. The "younger" isolated animals displayed greater stereotypy than group-reared and "older" isolated animals. Rearing environment and age, as main factors, did not have significant influence on drug-induced stereotypy.

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Year:  1984        PMID: 6542229     DOI: 10.1016/s0091-3057(84)80056-8

Source DB:  PubMed          Journal:  Pharmacol Biochem Behav        ISSN: 0091-3057            Impact factor:   3.533


  5 in total

Review 1.  Have studies of the developmental regulation of behavioral phenotypes revealed the mechanisms of gene-environment interactions?

Authors:  F Scott Hall; Maria T G Perona
Journal:  Physiol Behav       Date:  2012-05-27

2.  Effects of early environmental experience on self-administration of amphetamine and barbital.

Authors:  B Zimmerberg; M B Brett
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

3.  Comparison of the effects of dopamine agonists on self-stimulation of the hypothalamus with lesioning of mesolimbic brain structures in rats reared in conditions of social isolation.

Authors:  G N Panchenko; A A Lebedev; P D Shabanov
Journal:  Neurosci Behav Physiol       Date:  1998 Mar-Apr

4.  Increased sensitivity to amphetamine and reward-related stimuli following social isolation in rats: possible disruption of dopamine-dependent mechanisms of the nucleus accumbens.

Authors:  G H Jones; C A Marsden; T W Robbins
Journal:  Psychopharmacology (Berl)       Date:  1990       Impact factor: 4.530

5.  Social deprivation enhances the vulnerability of male Wistar rats to stressor- and amphetamine-induced behavioral sensitization.

Authors:  S H Ahmed; L Stinus; M Le Moal; M Cador
Journal:  Psychopharmacology (Berl)       Date:  1995-01       Impact factor: 4.530

  5 in total

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