Literature DB >> 6539933

Comparison of the stimulatory effects of eight antiparkinsonian drugs.

P L Goldschmidt, L Savary, P Simon.   

Abstract

The effects of eight antiparkinsonian anticholinergic drugs on motor activity in mice were studied. Trihexyphenidyl, biperiden, benztropine, etybenztropine, procyclidine and tropacine clearly stimulated motor activity. Orphenadrine did not change motor activity, and profenamine had sedative properties. The classification of these drugs by order of their effect on this animal model does not agree with the classification proposed by Deniker et al (1980).

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Year:  1984        PMID： 6539933     DOI： 10.1016/0278-5846(84)90162-3

Source DB:  PubMed          Journal:  Prog Neuropsychopharmacol Biol Psychiatry        ISSN： 0278-5846            Impact factor:   5.067


  3 in total

1.  Decreased prepulse inhibition and increased sensitivity to muscarinic, but not dopaminergic drugs in M5 muscarinic acetylcholine receptor knockout mice.

Authors:  Morgane Thomsen; Gitta Wörtwein; Anders Fink-Jensen; David P D Woldbye; Jürgen Wess; S Barak Caine
Journal:  Psychopharmacology (Berl)       Date:  2007-02-20       Impact factor: 4.415

2.  Reduction of imines with a reusable bimetallic PdCo-Fe3O4 catalyst at room temperature under atmospheric pressure of H2.

Authors:  Sabyuk Yang; Byeong Moon Kim
Journal:  RSC Adv       Date:  2022-01-18       Impact factor: 3.361

3.  Identification of key genes and pathways in chronic rhinosinusitis with nasal polyps and asthma comorbidity using bioinformatics approaches.

Authors:  Mingming Wang; Shuangmei Tang; Xiaoqi Yang; Xinyu Xie; Yang Luo; Shaojuan He; Xuezhong Li; Xin Feng
Journal:  Front Immunol       Date:  2022-08-17       Impact factor: 8.786
  3 in total

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