Literature DB >> 6538860

Evidence for polygenic epistatic interactions in man?

A C Heath, N G Martin, L J Eaves, D Loesch.   

Abstract

Studies of multifactorial inheritance in man have ignored nonadditive gene action or attributed it entirely to dominance. Reanalyses of dermatoglyphic data on monozygotic and dizygotic twins, siblings and parents and offspring suggest that a substantial proportion of variation in total finger pattern intensity is due to epistatic interactions between additive genetic deviations, not dominance. Bootstrapping and power simulations support this interpretation of the data. We believe this is the strongest evidence so far for polygenic epistasis in man.

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Year:  1984        PMID： 6538860      PMCID： PMC1202301     

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  7 in total

1.  Testing models for variation in intelligence.

Authors:  L J Eaves
Journal:  Heredity (Edinb)       Date:  1975-02       Impact factor: 3.821

2.  Causal analysis of academic performance.

Authors:  D C Rao; N E Morton; R C Elston; S Yee
Journal:  Behav Genet       Date:  1977-03       Impact factor: 2.805

3.  Resolution of cultural and biological inheritance by path analysis.

Authors:  D C Rao; N E Morton; S Yee
Journal:  Am J Hum Genet       Date:  1976-05       Impact factor: 11.025

4.  Multifactorial inheritance with cultural transmission and assortative mating. II. a general model of combined polygenic and cultural inheritance.

Authors:  C R Cloninger; J Rice; T Reich
Journal:  Am J Hum Genet       Date:  1979-03       Impact factor: 11.025

5.  Comparison of the biometrical genetical, MAVA, and classical approaches to the analysis of human behavior.

Authors:  J L Jinks; D W Fulker
Journal:  Psychol Bull       Date:  1970-05       Impact factor: 17.737

6.  Path analysis under generalized assortative mating. II. American I.Q.

Authors:  D C Rao; N E Morton; J M Lalouel; R Lew
Journal:  Genet Res       Date:  1982-04       Impact factor: 1.588

7.  Path analysis under generalized assortative mating. I. Theory.

Authors:  D C Rao; N E Morton; C R Cloninger
Journal:  Genet Res       Date:  1979-04       Impact factor: 1.588
  7 in total
  6 in total

1.  Fixed and random effects in the variation of the finger ridge count: a study of fragile-X families.

Authors:  D Z Loesch; R M Huggins
Journal:  Am J Hum Genet       Date:  1992-05       Impact factor: 11.025

2.  The Augmented Classical Twin Design: Incorporating Genome-Wide Identity by Descent Sharing Into Twin Studies in Order to Model Violations of the Equal Environments Assumption.

Authors:  Liang-Dar Hwang; Brittany L Mitchell; Sarah E Medland; Nicholas G Martin; Michael C Neale; David M Evans
Journal:  Behav Genet       Date:  2021-02-13       Impact factor: 2.805

3.  Combinatorial Methods for Epistasis and Dominance.

Authors:  Serge Sverdlov; Elizabeth Thompson
Journal:  J Comput Biol       Date:  2016-11-21       Impact factor: 1.479

4.  Age at menarche as a fitness trait: nonadditive genetic variance detected in a large twin sample.

Authors:  S A Treloar; N G Martin
Journal:  Am J Hum Genet       Date:  1990-07       Impact factor: 11.025

5.  Genetic and environmental factors in primary dysmenorrhea and its relationship to anxiety, depression, and neuroticism.

Authors:  J L Silberg; N G Martin; A C Heath
Journal:  Behav Genet       Date:  1987-07       Impact factor: 2.805

6.  No decline in assortative mating for educational level.

Authors:  A C Heath; K Berg; L J Eaves; M H Solaas; J Sundet; W E Nance; L A Corey; P Magnus
Journal:  Behav Genet       Date:  1985-07       Impact factor: 2.805
  6 in total

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