Literature DB >> 653835

Cocarcinogenic and irritant factors of Euphorbia esula L. latex.

R R Upadhyay, F Bakhtavar, M Ghaisarzadeh, J Tilabi.   

Abstract

The latex of (Euphorbia esula) has been found to contain highly skin irritant and inflammatory ingenol-3delta 2,4,6,8,10 pentene tetradecanoate and another factor, ingenol-3-dodecanoate, which is less irritating but which can be responsible for the cocarcinogenic activity exhibited by the latex preparation in the mice back skin experiment.

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Year:  1978        PMID: 653835     DOI: 10.1177/030089167806400112

Source DB:  PubMed          Journal:  Tumori        ISSN: 0300-8916


  4 in total

1.  Toxic and aversive diterpenes of Euphorbia esula.

Authors:  Fathi T Halaweish; Scott Kronberg; Mindy B Hubert; James A Rice
Journal:  J Chem Ecol       Date:  2002-08       Impact factor: 2.626

2.  Rodent and ruminant ingestive response to flavonoids in Euphorbia esula.

Authors:  F Halaweish; S Kronberg; J A Rice
Journal:  J Chem Ecol       Date:  2003-05       Impact factor: 2.626

3.  Potential aversive compounds in leafy spurge for ruminants and rats.

Authors:  S L Kronberg; W C Lynch; C D Cheney; J W Walker
Journal:  J Chem Ecol       Date:  1995-10       Impact factor: 2.626

4.  Ruminal metabolism of leafy spurge in sheep and goats: A potential explanation for differential foraging on spurge by sheep, goats, and cattle.

Authors:  S L Kronberg; J W Walker
Journal:  J Chem Ecol       Date:  1993-09       Impact factor: 2.626

  4 in total

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