Literature DB >> 6536816

Proliferative vitreoretinopathy: the rabbit cell injection model for screening of antiproliferative drugs.

P Wiedemann, N Sorgente, S J Ryan.   

Abstract

Injection into the rabbit vitreous of cultured cells results in a condition that mimics some of the features of proliferative vitreoretinopathy (PVR) in man. Because of its simplicity and reproducibility, this model is especially useful for screening drugs that may control or inhibit intraocular cell proliferation. The cell injection model of PVR is reviewed, and some modifications are described.

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Mesh:

Year:  1984        PMID: 6536816     DOI: 10.1016/0160-5402(84)90008-1

Source DB:  PubMed          Journal:  J Pharmacol Methods        ISSN: 0160-5402


  4 in total

1.  Evaluation of radiation therapy for experimental proliferative vitreoretinopathy in rabbits.

Authors:  S Kuriyama; T Ohuchi; N Yoshimura; Y Honda; M Hiraoka; M Abe
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1990       Impact factor: 3.117

Review 2.  Proliferative vitreoretinopathy--is it anything more than wound healing at the wrong place?

Authors:  M Weller; P Wiedemann; K Heimann
Journal:  Int Ophthalmol       Date:  1990-03       Impact factor: 2.031

3.  Intravitreal injection of fibroblasts: the pathological effects on the ocular tissues of the rabbit following an intravitreal injection of autologous skin fibroblasts.

Authors:  C A Hitchins; I Grierson
Journal:  Br J Ophthalmol       Date:  1988-07       Impact factor: 4.638

Review 4.  Rho-Kinase/ROCK as a Potential Drug Target for Vitreoretinal Diseases.

Authors:  Muneo Yamaguchi; Shintaro Nakao; Mitsuru Arima; Iori Wada; Yoshihiro Kaizu; Feng Hao; Shigeo Yoshida; Koh-Hei Sonoda
Journal:  J Ophthalmol       Date:  2017-05-10       Impact factor: 1.909

  4 in total

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