Literature DB >> 6532009

Potentials of capillary gas chromatography in toxicology today.

M Bogusz, J P Franke, R A de Zeeuw.   

Abstract

The usefulness, the applicability and the limitations of capillary gas chromatography in various types of toxicological analysis were discussed. Technical parameters of capillary gas chromatography, such as type of injector, type of column with regard to material, size, and stationary phase were assessed in view of the requirements of toxicological analysis. The main advantage of capillary gas chromatography, i.e. high separation power, is unfortunately counterbalanced by low loadability and/or speed of analysis. In the present situation capillary gas chromatography is a method of choice in drug screening despite some disadvantages, but in drug-oriented analysis the conventional chromatography on packed; columns is probably more useful.

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Year:  1984        PMID: 6532009     DOI: 10.1007/bf00198649

Source DB:  PubMed          Journal:  Z Rechtsmed        ISSN: 0044-3433


  14 in total

1.  Capillary gas chromatography on fused silica columns with splitless injection: the determination of phenobarbital in blood plasma.

Authors:  J P Franke; J Wijsbeek; R A de Zeeuw
Journal:  Pharm Weekbl Sci       Date:  1983-08-26

Review 2.  Forensic science.

Authors:  T A Brettell; R Saferstein
Journal:  Anal Chem       Date:  1983-04       Impact factor: 6.986

3.  Identification of basic drugs in urine by dual fused silica capillary column GC.

Authors:  G W Hime; L R Bednarczyk
Journal:  J Anal Toxicol       Date:  1982 Sep-Oct       Impact factor: 3.367

4.  Combined use of fused silica capillary columns and nitrogen-phosphorus detection for the toxicological analysis of illicit heroin samples.

Authors:  P Demedts; M Van den Heede; J Van der Verren; A Heyndrickx
Journal:  J Anal Toxicol       Date:  1982 Jan-Feb       Impact factor: 3.367

5.  Identification of drugs using capillary gas liquid chromatography.

Authors:  B Caddy; C B Kidd; S C Leung
Journal:  J Forensic Sci Soc       Date:  1982-01

Review 6.  Gas-liquid chromatographic retention indices of 1318 substances of toxicological interest on SE-30 or OV-1 stationary phase.

Authors:  R E Ardrey; A C Moffat
Journal:  J Chromatogr       Date:  1981-12-25

7.  Determination of opiates in biological samples by glass capillary gas chromatography with electron-capture detection.

Authors:  P O Edlund
Journal:  J Chromatogr       Date:  1981-02-06

8.  Gas--liquid chromatographic retention indices of 296 non-drug substances on SE-30 or OV-1 likely to be encountered in toxicological analyses.

Authors:  J D Ramsey; T D Lee; M D Osselton; A C Moffat
Journal:  J Chromatogr       Date:  1980-03-28

9.  Detection and identification of gasoline in tissues by capillary GC using pattern recognition techniques.

Authors:  B Shankles; S B Weinberg; L A Dal Cortivo
Journal:  J Anal Toxicol       Date:  1982 Sep-Oct       Impact factor: 3.367

10.  Applicability of capillary gas chromatography to systematic toxicological analysis: occurrence of concentration-dependent retention behavior.

Authors:  M Bogusz; J Wijsbeek; J P Franke; R A de Zeeuw
Journal:  J Anal Toxicol       Date:  1983 Jul-Aug       Impact factor: 3.367

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  1 in total

Review 1.  Modern screening strategies in analytical toxicology with special regard to new benzodiazepines.

Authors:  H Schütz
Journal:  Z Rechtsmed       Date:  1988
  1 in total

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