UNLABELLED: The purpose of the present work was to answer two questions: does the human gallbladder empty in the fasting state, and, if so, is the emptying related to a specific phase of the activity in the gastrointestinal tract? The material consisted of nine healthy volunteers and the motility recordings were done with a perfused low-compliance system. Gallbladder emptying was recorded by the use of scintigraphy with 99mTc-HIDA. Eleven activity fronts were observed, and seven periods of gallbladder emptying were recorded. Reduction in counts over the gallbladder ranged from 8% to 32%. All emptyings took place in connection with phase-II activity in the intestine. Three were in close proximity to the following phase-III activity, and the other four occurred early in a phase II. Four activity fronts were not accompanied by output of bile. CONCLUSIONS: bile output from the gallbladder occurs in fasting humans, and gallbladder emptying takes place in connection with phase-II activity in the intestine but not always in close connection with the following phase-III activity.
UNLABELLED: The purpose of the present work was to answer two questions: does the human gallbladder empty in the fasting state, and, if so, is the emptying related to a specific phase of the activity in the gastrointestinal tract? The material consisted of nine healthy volunteers and the motility recordings were done with a perfused low-compliance system. Gallbladder emptying was recorded by the use of scintigraphy with 99mTc-HIDA. Eleven activity fronts were observed, and seven periods of gallbladder emptying were recorded. Reduction in counts over the gallbladder ranged from 8% to 32%. All emptyings took place in connection with phase-II activity in the intestine. Three were in close proximity to the following phase-III activity, and the other four occurred early in a phase II. Four activity fronts were not accompanied by output of bile. CONCLUSIONS: bile output from the gallbladder occurs in fasting humans, and gallbladder emptying takes place in connection with phase-II activity in the intestine but not always in close connection with the following phase-III activity.
Authors: M F Stolk; K J Van Erpecum; T L Peeters; M Samsom; A J Smout; L M Akkermans; G P Vanberge-Henegouwen Journal: Dig Dis Sci Date: 2001-06 Impact factor: 3.199
Authors: Y C Luiking; T L Peeters; M F Stolk; V B Nieuwenhuijs; P Portincasa; I Depoortere; G P van Berge Henegouwen; L M Akkermans Journal: Gut Date: 1998-06 Impact factor: 23.059
Authors: M F Stolk; K J van Erpecum; H P Koppeschaar; M Samsom; A J Smout; L M Akkermans; T L Peeters; G P vanBerge-Henegouwen Journal: Gut Date: 1995-05 Impact factor: 23.059