Literature DB >> 6529170

[Megacolon in adults. Apropos of 76 cases].

R Parc, J L Berrod, J Tussiot, J Loygue.   

Abstract

27 patients with Hirschsprung's disease and 49 patients with idiopathic megacolon were followed for a period ranging between 6 months and 15 years. The diagnosis is essentially based on the barium enema and functional ano-rectal investigations. Duhamel's operation was performed in 26 patients with Hirschsprung's disease and in 34 patients with idiopathic megacolon. There was no mortality, but 10 cases of pelvic suppuration required colostomy, 9 of which were temporary. 8 cases of anastomotic stenosis developed as a late complication, but they were easily dilated by a simple surgical procedure. One patient developed sexual dysfunction (retrograde ejaculation). A good result was obtained in all patients with Hirschsprung's disease, except for one case of adynamic colon. Two patients with idiopathic megacolon were lost to follow-up. All but two of the remaining patients obtained a good or excellent result. Other operations were performed for idiopathic megacolon: 6 sphincterotomies, with 3 successes and 3 failures; 15 sigmoidectomies, including 3 with sub-peritoneal anastomosis (State's operation). There were 5 good results, 6 mediocre results and 4 failures which subsequently required a Duhamel's operation. Other techniques were performed more rarely: Swenson's operation with a short-term technical failure, 3 side-to-side ileo-sigmoid anastomoses with 3 failures which required a sub-total colectomy with ileo-sigmoid anastomosis. The longterm result was mediocre. The trans-rectal, colo-anal descent of the colon therefore appears to be the treatment of choice in megacolon in adults of whatever cause.

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Year:  1984        PMID: 6529170

Source DB:  PubMed          Journal:  Ann Gastroenterol Hepatol (Paris)        ISSN: 0066-2070


  7 in total

Review 1.  Hirschsprung disease, associated syndromes, and genetics: a review.

Authors:  J Amiel; S Lyonnet
Journal:  J Med Genet       Date:  2001-11       Impact factor: 6.318

2.  Idiopathic megarectum treated by Duhamel's operation.

Authors:  G Gagliardi; M J Hershman; P R Hawley
Journal:  J R Soc Med       Date:  1992-06       Impact factor: 5.344

Review 3.  Surgery for idiopathic megarectum and megacolon.

Authors:  G Stabile; M A Kamm
Journal:  Int J Colorectal Dis       Date:  1991-08       Impact factor: 2.571

Review 4.  Systematic review of surgical options for idiopathic megarectum and megacolon.

Authors:  Marc A Gladman; S Mark Scott; Peter J Lunniss; Norman S Williams
Journal:  Ann Surg       Date:  2005-04       Impact factor: 12.969

5.  Results of stoma formation for idiopathic megarectum and megacolon.

Authors:  G Stabile; M A Kamm; P R Hawley; J E Lennard-Jones
Journal:  Int J Colorectal Dis       Date:  1992-06       Impact factor: 2.571

Review 6.  The developmental etiology and pathogenesis of Hirschsprung disease.

Authors:  Naomi E Butler Tjaden; Paul A Trainor
Journal:  Transl Res       Date:  2013-03-22       Impact factor: 7.012

7.  Colectomy for idiopathic megarectum and megacolon.

Authors:  G Stabile; M A Kamm; P R Hawley; J E Lennard-Jones
Journal:  Gut       Date:  1991-12       Impact factor: 23.059

  7 in total

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