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Literature DB >> 6524516

On the presence of H1-receptors in various sections of guinea-pig heart: a correlation between binding and functional studies.

F Bennardini, S Amerini, F Franconi, F Ledda, L Mantelli, R Matucci, A Mugelli, C Sorbi.

Abstract

The binding of 3H-mepyramine in different sections of guinea-pig heart was examined. 3H-mepyramine binds to a single class of binding sites to guinea-pig ventricular membranes and to right atrial suspension with an apparent dissociation constant (Kd) of 4.35 nM and 14.90 nM respectively. When treated as those obtained from the right atrium, the left atrial suspensions do not seem to bind 3H-mepyramine specifically.

Entities: Chemical Species

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Year: 1984 PMID： 6524516 DOI： 10.1007/bf01972344

Source DB: PubMed Journal: Agents Actions ISSN： 0065-4299

15 in total

Review 1. Cardiac histamine receptors.

Authors: R Levi; G Allan; J H Zavecz
Journal: Fed Proc Date: 1976-06

Review 2. Physiology and pharmacology of cardiac histamine.

Authors: P F Mannaioni
Journal: Arch Int Pharmacodyn Ther Date: 1972-04

3. Characterization of [3H]mepyramine binding to the longitudinal muscle of guinea pig small intestine.

Authors: S J Hill; J M Young
Journal: Mol Pharmacol Date: 1981-05 Impact factor: 4.436

4. Solubilization of a calcium dependent adenosine triphosphatase from rat heart sarcolemma.

Authors: N S Dhalla; M B Anand-Srivastava; B S Tuana; R L Khandelwal
Journal: J Mol Cell Cardiol Date: 1981-04 Impact factor: 5.000

5. Histamine receptors in the human heart.

Authors: R Ginsburg; M R Bristow; E B Stinson; D C Harrison
Journal: Life Sci Date: 1980-06-30 Impact factor: 5.037

6. Differentiation of H1- and H2-receptors mediating positive chrono- and inotropic responses to histamine on atrial preparations of the guinea-pig.

Authors: D Reinhardt; J Wagner; H J Schümann
Journal: Agents Actions Date: 1974-10

7. Differentiation of the roles of histamine H1- and H2-receptors in the mediation of the effects of histamine in the isolated working heart of the guinea-pig.

Authors: S B Flynn; R W Gristwood; D A Owen
Journal: Br J Pharmacol Date: 1979-01 Impact factor: 8.739

1. Identification and characterization of histamine H1- and H2-receptors in guinea-pig left atrial membranes by [3H]-mepyramine and [3H]-tiotidine binding.

Authors: Y Hattori; M Endou; S Gando; M Kanno
Journal: Br J Pharmacol Date: 1991-06 Impact factor: 8.739

2. Indirect evidence for a role of phosphatidylinositol turnover in the cardiac response to H1-receptor stimulation.

Authors: L Mantelli; F Ledda; L Capanni; V Corti
Journal: Agents Actions Date: 1988-07

2 in total