Literature DB >> 6523691

Effect of feeding on the fate of orally administered phenylbutazone, trimethoprim and sulphadiazine in the horse.

J A Bogan, A Galbraith, P Baxter, N M Ali, S E Marriner.   

Abstract

Phenylbutazone, sulphadiazine and trimethoprim were administered to three horses on two occasions, recently fed and unfed, and the effect of feeding on the pharmacokinetics of the three drugs assessed. The mean peak concentrations of phenylbutazone and trimethoprim were reduced by feeding by 34 and 75 per cent, respectively. The pharmacokinetics of sulphadiazine were not significantly affected.

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Year:  1984        PMID： 6523691     DOI： 10.1136/vr.115.23.599

Source DB:  PubMed          Journal:  Vet Rec        ISSN： 0042-4900            Impact factor:   2.695


  2 in total

1.  Bioavailability and pharmacokinetics of sulphadiazine, N4-acetylsulphadiazine and trimethoprim following intravenous and intramuscular administration of a sulphadiazine/trimethoprim combination in sheep.

Authors:  G C Batzias; G A Delis; M Koutsoviti-Papadopoulou
Journal:  Vet Res Commun       Date:  2005-11       Impact factor: 2.459

Review 2.  Equine Protozoal Myeloencephalitis: An Updated Consensus Statement with a Focus on Parasite Biology, Diagnosis, Treatment, and Prevention.

Authors:  S M Reed; M Furr; D K Howe; A L Johnson; R J MacKay; J K Morrow; N Pusterla; S Witonsky
Journal:  J Vet Intern Med       Date:  2016-02-09       Impact factor: 3.333
  2 in total

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