Literature DB >> 6521582

[Increase of bile acid reabsorption following total small intestine resection in the rat].

P Martinez, D Gutstein, I Nuñez de Castro, C Vara-Thorbeck.   

Abstract

Bile salts undergo an enterohepatic circulation. The relative distribution of labelled cholic acid in portal blood, enterocytes, intestinal contents and feces, following intravenous injection of (carboxylic-14C) cholic acid, can be considered as an indication of the absorptive capacity of the epithelium cells. Seven days after a massive small intestinal resection (60-80 cm), the animal weight and the bile salt absorption were significantly decreased. Nevertheless, thirty days after the operation, weight and radioactivities reached the values found in the controls: in portal and cava blood, liver, intestinal contents and feces. An increase of the absorptive capacity of the intestinal epithelial cells was also observed.

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Year:  1984        PMID: 6521582     DOI: 10.1007/bf01261056

Source DB:  PubMed          Journal:  Langenbecks Arch Chir        ISSN: 0023-8236


  13 in total

1.  Postprandial serum bile acids in healthy man. Evidence for differences in absorptive pattern between individual bile acids.

Authors:  B Angelin; I Björkhem
Journal:  Gut       Date:  1977-08       Impact factor: 23.059

Review 2.  The enterohepatic circulation of bile acids in man.

Authors:  A F Hofmann
Journal:  Clin Gastroenterol       Date:  1977-01

3.  The effect of resection of the small intestine upon the fine structure of the intestinal epithelium.

Authors:  M D Tilson; H K Wright
Journal:  Surg Gynecol Obstet       Date:  1972-06

4.  Mechanisms for the intestinal absorption of bile acids.

Authors:  J M Dietschy
Journal:  J Lipid Res       Date:  1968-05       Impact factor: 5.922

5.  Studies of small bowel adaptation after intestinal resection in the rat.

Authors:  E Weser; M H Hernandez
Journal:  Gastroenterology       Date:  1971-01       Impact factor: 22.682

Review 6.  Part I. The etiology and pathogenesis of gallstones.

Authors:  D M Small
Journal:  Adv Surg       Date:  1976

7.  Resection of the small intestine in rats. 3. Morphological changes in the intestinal tract.

Authors:  K Nygaard
Journal:  Acta Chir Scand       Date:  1967

8.  Colonic absorption of unconjugated bile acids: perfusion studies in man.

Authors:  H S Mekhjian; S F Phillips; A F Hofmann
Journal:  Dig Dis Sci       Date:  1979-07       Impact factor: 3.199

9.  Physiological factors influencing serum bile acid levels.

Authors:  M Ponz De Leon; G M Murphy; R H Dowling
Journal:  Gut       Date:  1978-01       Impact factor: 23.059

10.  Enterohepatic circulation rates of cholic acid and chenodeoxycholic acid in man.

Authors:  K A Einarsson; S M Gundy; W G Hardison
Journal:  Gut       Date:  1979-12       Impact factor: 23.059

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