Literature DB >> 6520618

Improvement of ataxia in alcoholic cerebellar atrophy through alcohol abstinence.

H C Diener, J Dichgans, M Bacher, B Guschlbauer.   

Abstract

Postural instability was measured and short, medium and long latency EMG responses to angular displacement of the ankle were recorded from leg muscles in a group of 17 alcoholics who presented with clinical signs of cerebellar atrophy of the anterior lobe. Recordings were performed twice (average interval 18.5 months) to determine the effects of continued drinking versus abstinence on the signs of the cerebellar damage. Patients who were abstinent (n = 11) exhibited a significant, sometimes dramatic decrease of body sway whereas patients who continued drinking (n = 6) showed increased body sway when the eyes were closed. Short and medium latency EMG responses were unaltered in both groups of patients. The integral of the long latency response of the antagonist tended to increase with continued abuse and to decrease in abstinent patients.

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Year:  1984        PMID: 6520618     DOI: 10.1007/bf00313662

Source DB:  PubMed          Journal:  J Neurol        ISSN: 0340-5354            Impact factor:   4.849


  15 in total

1.  Cerebellar dysfunction associated with chronic alcoholism.

Authors:  J B DECKER; C E WELLS; F McDOWELL
Journal:  Neurology       Date:  1959-05       Impact factor: 9.910

2.  Postural sway in normals and atactic patients: analysis of the stabilising and destabilizing effects of vision.

Authors:  J Dichgans; K H Mauritz; J H Allum; T Brandt
Journal:  Agressologie       Date:  1976

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Authors:  W J DIXON; A M MOOD
Journal:  J Am Stat Assoc       Date:  1946-12       Impact factor: 5.033

4.  Coupled stretch reflexes in ankle muscles: an evaluation of the contributions of active muscle mechanisms to human posture stability.

Authors:  J H Allum; H J Büdingen
Journal:  Prog Brain Res       Date:  1979       Impact factor: 2.453

5.  Quantification of postural sway in normals and patients with cerebellar diseases.

Authors:  H C Diener; J Dichgans; M Bacher; B Gompf
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1984-02

6.  Computerized tomography of the brain in chronic alcoholism: a Survey and follow-up study.

Authors:  M A Ron; W Acker; G K Shaw; W A Lishman
Journal:  Brain       Date:  1982-09       Impact factor: 13.501

7.  [Atrophy of the cerebellar vermis and chronic alcoholism. Clinical-anatomical study of 44 cases].

Authors:  J Stork
Journal:  Schweiz Arch Neurol Neurochir Psychiatr       Date:  1967

8.  Quantitative analysis of stance in late cortical cerebellar atrophy of the anterior lobe and other forms of cerebellar ataxia.

Authors:  K H Mauritz; J Dichgans; A Hufschmidt
Journal:  Brain       Date:  1979-09       Impact factor: 13.501

9.  Variability of postural "reflexes" in humans.

Authors:  H C Diener; F Bootz; J Dichgans; W Bruzek
Journal:  Exp Brain Res       Date:  1983       Impact factor: 1.972

10.  Cortical cerebellar degeneration associated with a specific disorder of standing and locomotion.

Authors:  B P Silfverskiöld
Journal:  Acta Neurol Scand       Date:  1977-04       Impact factor: 3.209

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  19 in total

1.  Persistent but less severe ataxia in long-term versus short-term abstinent alcoholic men and women: a cross-sectional analysis.

Authors:  Stan Smith; George Fein
Journal:  Alcohol Clin Exp Res       Date:  2011-09-15       Impact factor: 3.455

2.  Mechanisms of postural control in alcoholic men and women: biomechanical analysis of musculoskeletal coordination during quiet standing.

Authors:  Edith V Sullivan; Jessica Rose; Adolf Pfefferbaum
Journal:  Alcohol Clin Exp Res       Date:  2009-12-17       Impact factor: 3.455

Review 3.  Ataxia.

Authors:  Umar Akbar; Tetsuo Ashizawa
Journal:  Neurol Clin       Date:  2015-02       Impact factor: 3.806

4.  Long latency EMG responses in hand and leg muscles: cerebellar disorders.

Authors:  H H Friedemann; J Noth; H C Diener; M Bacher
Journal:  J Neurol Neurosurg Psychiatry       Date:  1987-01       Impact factor: 10.154

5.  Improvement of atactic syndrome after longer periods of alcohol abstinence.

Authors:  F Leblhuber; F Reisecker; W Pühringer
Journal:  J Neurol       Date:  1985       Impact factor: 4.849

6.  Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation.

Authors:  Dora Lippai; Shashi Bala; Jan Petrasek; Timea Csak; Ivan Levin; Evelyn A Kurt-Jones; Gyongyi Szabo
Journal:  J Leukoc Biol       Date:  2013-04-26       Impact factor: 4.962

7.  Improvement in memory and static balance with abstinence in alcoholic men and women: selective relations with change in brain structure.

Authors:  Margaret J Rosenbloom; Torsten Rohlfing; Anne W O'Reilly; Stephanie A Sassoon; Adolf Pfefferbaum; Edith V Sullivan
Journal:  Psychiatry Res       Date:  2007-04-03       Impact factor: 3.222

8.  Incidence of peripheral neuropathy and cerebellar ataxia in chronic alcoholics.

Authors:  E Scholz; H C Diener; J Dichgans; H D Langohr; W Schied; A Schupmann
Journal:  J Neurol       Date:  1986-08       Impact factor: 4.849

9.  Pontocerebellar volume deficits and ataxia in alcoholic men and women: no evidence for "telescoping".

Authors:  Edith V Sullivan; Torsten Rohlfing; Adolf Pfefferbaum
Journal:  Psychopharmacology (Berl)       Date:  2009-11-27       Impact factor: 4.530

Review 10.  Neurologic effects of alcoholism.

Authors:  I Diamond; R O Messing
Journal:  West J Med       Date:  1994-09
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