Literature DB >> 6520617

Leigh's syndrome in an adult.

E Masó, I Ferrer, J Herraiz, J Roquer, S Serrano.   

Abstract

A 55-year-old man with a subacute onset of slurred speech, ataxia, nystagmus, extrapyramidal rigidity, decreased tendon reflexes, vomiting, bilateral optic atrophy, and clonic jerks died of bronchopneumonia and respiratory failure. Neuropathological examination showed lesions characteristic of subacute necrotizing encephalopathy. Clinicopathological observations of reported cases of Leigh's syndrome in the adult are reviewed.

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Year:  1984        PMID: 6520617     DOI: 10.1007/bf00313661

Source DB:  PubMed          Journal:  J Neurol        ISSN: 0340-5354            Impact factor:   4.849


  13 in total

1.  Leigh's disease in an adult with evidence of "inhibitor factor" in family members.

Authors:  W O Whetsell; A Plaitakis
Journal:  Ann Neurol       Date:  1978-06       Impact factor: 10.422

2.  [Clinical and pathological description of Gayet-Wernicke encephalopathy and the adult form of Leigh's encephalopathy].

Authors:  J J Martin
Journal:  Acta Neurol Belg       Date:  1972 Sep-Oct       Impact factor: 2.396

3.  Subacute necrotizing encephalopathy (Leigh) in an adult.

Authors:  J Ulrich; C Fankhauser-Mauri
Journal:  Eur Neurol       Date:  1978       Impact factor: 1.710

4.  [The adult form of Leigh's necrotizing encephalopathy with chronic evolution. Its comparison with the infantile and juvenile forms].

Authors:  C Solheid; N Stoupel; J J Martin
Journal:  Acta Neurol Belg       Date:  1971 May-Jun       Impact factor: 2.396

5.  Familial subacute necrotizing encephalomyelopathy of the adult form (adult Leigh syndrome).

Authors:  H Kalimo; P O Lundberg; Y Olsson
Journal:  Ann Neurol       Date:  1979-09       Impact factor: 10.422

6.  Chronic Leigh Disease: a genetic and biochemical study.

Authors:  A Plaitakis; W O Whetsell; J R Cooper; M D Yahr
Journal:  Ann Neurol       Date:  1980-04       Impact factor: 10.422

7.  Neuropathologic changes in suckling and weanling rats with pyrithiamine-induced thiamine deficiency.

Authors:  N Horita; A Okuno; Y Izumiyama
Journal:  Acta Neuropathol       Date:  1983       Impact factor: 17.088

8.  Early edematous lesion of pyrithiamine induced acute thiamine deficient encephalopathy in the mouse.

Authors:  I Watanabe; S Kanabe
Journal:  J Neuropathol Exp Neurol       Date:  1978 Jul-Aug       Impact factor: 3.685

9.  Model of Wernicke's encephalopathy.

Authors:  J C Troncoso; M V Johnston; K M Hess; J W Griffin; D L Price
Journal:  Arch Neurol       Date:  1981-06

10.  Leigh's syndrome: the adult form of subacute necrotizing encephalomyelopathy with predilection for the brainstem.

Authors:  J C Sipe
Journal:  Neurology       Date:  1973-10       Impact factor: 9.910

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  5 in total

1.  Acute necrotizing encephalopathy with widespread edematous lesions of symmetrical distribution.

Authors:  M Mizuguchi; M Tomonaga; T Fukusato; M Asano
Journal:  Acta Neuropathol       Date:  1989       Impact factor: 17.088

2.  Medical treatment with thiamine, coenzyme Q, vitamins E and C, and carnitine improved obstructive sleep apnea in an adult case of Leigh disease.

Authors:  Charalampos Mermigkis; Izolde Bouloukaki; Vasileios Mastorodemos; Andreas Plaitakis; Vangelis Alogdianakis; Nikolaos Siafakas; Sophia Schiza
Journal:  Sleep Breath       Date:  2013-02-07       Impact factor: 2.816

Review 3.  Neuropathology of thiamine deficiency disorders.

Authors:  J J Kril
Journal:  Metab Brain Dis       Date:  1996-03       Impact factor: 3.584

4.  Necrotising haemorrhagic encephalomyelopathy in an adult: Leigh's disease.

Authors:  G Delgado; J Gállego; T Tuñón; J J Zarranz; J A Villanueva
Journal:  J Neurol Neurosurg Psychiatry       Date:  1987-02       Impact factor: 10.154

5.  Leigh syndrome followed by parkinsonism in an adult with homozygous c.626C>T mutation in MTFMT.

Authors:  Dimitri M Hemelsoet; Arnaud V Vanlander; Joél Smet; Elise Vantroys; Marjan Acou; Ingeborg Goethals; Tom Sante; Sara Seneca; Bjorn Menten; Rudy Van Coster
Journal:  Neurol Genet       Date:  2018-11-27
  5 in total

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