Literature DB >> 6519180

Species-dependent differences in the nature of endothelium-derived vascular relaxing factor.

U Förstermann, G Trogisch, R Busse.   

Abstract

Effluents from perfused acetylcholine-relaxed endothelium segments of rabbit aorta (or canin femoral artery) contained endothelium-derived relaxing factors (EDRF) which dilated the endothelium-free segments of rabbit femoral artery (or side branches of canine femoral artery). The half-life of EDRF was 24 +/- 3 s for the rabbit and 49 +/- 5 s for the canine system. Nordihydroguaiaretic acid was less effective against the formation of canine EDRF than of rabbit EDRF. These findings suggest species differences in the nature of EDRF.

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Year:  1984        PMID： 6519180     DOI： 10.1016/0014-2999(84)90071-2

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  19 in total

1.  The inhibition of release of endothelium-derived relaxant factor by manoalide, a potent inhibitor of phospholipase A2.

Authors:  C J Long; H M Sarau; B A Berkowitz
Journal:  Br J Pharmacol       Date:  1987-12       Impact factor: 8.739

2.  Inhibition of endothelium-dependent smooth muscle relaxation by calmodulin antagonists.

Authors:  G Weinheimer; H Osswald
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1986-04       Impact factor: 3.000

3.  Elevated guanosine 3':5'-cyclic monophosphate mediates the depression of nitrovasodilator reactivity in endothelium-intact blood vessels.

Authors:  W F Jackson; R Busse
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1991-09       Impact factor: 3.000

4.  Selective inhibition by gossypol of endothelium-dependent relaxations augments relaxations to glyceryl trinitrate in rabbit coeliac artery.

Authors:  U Alheid; C Dudel; U Förstermann
Journal:  Br J Pharmacol       Date:  1987-09       Impact factor: 8.739

5.  The half-life of endothelium-derived relaxing factor released from bovine aortic endothelial cells in culture.

Authors:  J A Angus; T M Cocks
Journal:  J Physiol       Date:  1987-07       Impact factor: 5.182

Review 6.  The vascular endothelium: a survey of some newly evolving biochemical and physiological features.

Authors:  E Gerlach; S Nees; B F Becker
Journal:  Basic Res Cardiol       Date:  1985 Sep-Oct       Impact factor: 17.165

7.  Endothelium-dependent relaxation is independent of arachidonic acid release.

Authors:  P G Milner; N J Izzo; J Saye; A L Loeb; R A Johns; M J Peach
Journal:  J Clin Invest       Date:  1988-06       Impact factor: 14.808

8.  A comparison of the action of the endothelium-derived relaxant factor and the inhibitory factor from the bovine retractor penis on rabbit aortic smooth muscle.

Authors:  A Bowman; J S Gillespie; P Soares-da-Silva
Journal:  Br J Pharmacol       Date:  1986-01       Impact factor: 8.739

9.  Effect of phenobarbitone pretreatment upon endothelium-dependent relaxation to acetylcholine in rat superior mesenteric arterial bed.

Authors:  M D Randall; C R Hiley
Journal:  Br J Pharmacol       Date:  1988-07       Impact factor: 8.739

10.  Leptin's activity on the hydroxyl radical: a possible link to the oxidative stress-related endothelial vasodilation in patients with obstructive sleep apnea.

Authors:  Madalina Macrea; Thomas Martin; Zhenquan Jia; Hara Misra
Journal:  Lung       Date:  2013-05-21       Impact factor: 2.584
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