| Literature DB >> 6517550 |
J E Rudin, C W Norden, E M Shinners.
Abstract
For 177 gram-negative isolates, the MICs for ciprofloxacin ranged from 0.02 microgram/ml (Escherichia coli) to 0.31 microgram/ml (Pseudomonas aeruginosa). In time-kill curves, ciprofloxacin at 8 X the MIC almost completely killed 10(6) CFU of P. aeruginosa by 24 h. Ciprofloxacin at 4 X the MIC allowed bacterial regrowth by 24 h, with development of partial resistance to ciprofloxacin.Entities:
Mesh:
Substances:
Year: 1984 PMID: 6517550 PMCID: PMC179973 DOI: 10.1128/AAC.26.4.597
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191