Literature DB >> 6517492

Fluorometric assay of human serum carnosinase activity in normal children, adults and patients with myopathy.

K Bando, T Shimotsuji, H Toyoshima, C Hayashi, K Miyai.   

Abstract

A sensitive, accurate method has been established for the assay of serum carnosinase by measuring the fluorescence emitted from the L-histidine liberated on treatment with o-phthaldialdehyde. Using this method the serum values for normal adults, infants and children were measured. The mean value was very low in infants of less than 1 year old but increased with age, being almost the same in children aged 6 years or more as in adults. In adult men, the mean activity was 1.85 mumol/mL/h and in adult women it was 2.07 mumol/mL/h. Low activity was observed in patients with muscular dystrophy.

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Year:  1984        PMID: 6517492     DOI: 10.1177/000456328402100613

Source DB:  PubMed          Journal:  Ann Clin Biochem        ISSN: 0004-5632            Impact factor:   2.057


  10 in total

1.  CNDP1 knockout in zebrafish alters the amino acid metabolism, restrains weight gain, but does not protect from diabetic complications.

Authors:  Felix Schmöhl; Verena Peters; Claus Peter Schmitt; Gernot Poschet; Michael Büttner; Xiaogang Li; Tim Weigand; Tanja Poth; Nadine Volk; Jakob Morgenstern; Thomas Fleming; Peter P Nawroth; Jens Kroll
Journal:  Cell Mol Life Sci       Date:  2019-05-09       Impact factor: 9.261

2.  Common variants in CNDP1 and CNDP2, and risk of nephropathy in type 2 diabetes.

Authors:  T S Ahluwalia; E Lindholm; L C Groop
Journal:  Diabetologia       Date:  2011-05-15       Impact factor: 10.122

3.  Alcohol and muscle disease.

Authors:  V R Preedy; T J Peters
Journal:  J R Soc Med       Date:  1994-04       Impact factor: 5.344

4.  Association between CNDP1 genotype and diabetic nephropathy is sex specific.

Authors:  Antien L Mooyaart; Ana Zutinic; Stephan J L Bakker; Diana C Grootendorst; Nanne Kleefstra; Irene G M van Valkengoed; Stefan Böhringer; Henk J G Bilo; Friedo W Dekker; Jan Anthonie Bruijn; Gerjan Navis; Bart Janssen; Hans J Baelde; Emile De Heer
Journal:  Diabetes       Date:  2010-03-23       Impact factor: 9.461

5.  Intestinal absorption of the intact peptide carnosine in man, and comparison with intestinal permeability to lactulose.

Authors:  M L Gardner; K M Illingworth; J Kelleher; D Wood
Journal:  J Physiol       Date:  1991-08       Impact factor: 5.182

6.  Evidence for an essential role of intradimer interaction in catalytic function of carnosine dipeptidase II using electrospray-ionization mass spectrometry.

Authors:  Nobuaki Okumura; Jun Tamura; Toshifumi Takao
Journal:  Protein Sci       Date:  2015-11-25       Impact factor: 6.725

Review 7.  Carnosinase, diabetes mellitus and the potential relevance of carnosinase deficiency.

Authors:  Verena Peters; Johannes Zschocke; Claus P Schmitt
Journal:  J Inherit Metab Dis       Date:  2017-10-13       Impact factor: 4.982

8.  Feeding filaggrin: effects of l-histidine supplementation in atopic dermatitis.

Authors:  Siao Pei Tan; Simon B Brown; Christopher Em Griffiths; Richard B Weller; Neil K Gibbs
Journal:  Clin Cosmet Investig Dermatol       Date:  2017-10-05

9.  Allosteric inhibition of carnosinase (CN1) by inducing a conformational shift.

Authors:  Verena Peters; Claus P Schmitt; Tim Weigand; Kristina Klingbeil; Christian Thiel; Antje van den Berg; Vittorio Calabrese; Peter Nawroth; Thomas Fleming; Elisabete Forsberg; Andreas H Wagner; Markus Hecker; Giulio Vistoli
Journal:  J Enzyme Inhib Med Chem       Date:  2017-12       Impact factor: 5.051

Review 10.  Nutrigenomics: Opportunities & challenges for public health nutrition.

Authors:  V Sudhakar Reddy; Ravindranadh Palika; Ayesha Ismail; Raghu Pullakhandam; G Bhanuprakash Reddy
Journal:  Indian J Med Res       Date:  2018-11       Impact factor: 2.375

  10 in total

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