The maternal pheromone and brain development in the preweanling rat.

Preweanling rats selectively approach and consume pheromone-containing maternal feces. This selectivity suggests that the consumption of maternal feces might be important for the growing pup. Previous research suggested that such feces might promote brain development. A series of experiments was carried out in which pups were denied access to maternal feces. These pups were clearly inferior to control pups in brain growth and neurobehavioral maturation, as well as in the quantity of brain myelin.