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Literature DB >> 6513994

Live Blastomyces dermatitidis yeast-induced responses of immune and nonimmune human mononuclear cells.

Abstract

Peripheral blood mononuclear cells from humans with treated blastomycosis or from normal persons were cultured with live Blastomyces dermatitidis yeast. There was no inhibition of growth of the fungus in this suspension culture technique but morphologic and functional differences of the human cells were great between the two groups. Lymphocyte stimulation by live Blastomyces yeast was found in the patient group but not in the normal donors. These events add to the observations that cellular immunity is expressed in blastomycosis.

Entities: Disease Species

Mesh：

Substances：
Thymidine

Year: 1984 PMID： 6513994 DOI： 10.1007/bf00436902

Source DB: PubMed Journal: Mycopathologia ISSN： 0301-486X Impact factor: 2.574

21 in total

1. Variation in lymphocyte reactivity to histoplasmin during the course of chronic pulmonary histoplasmosis.

Authors: R H Alford; R A Goodwin
Journal: Am Rev Respir Dis Date: 1973-07

2. Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

Authors: A Böyum
Journal: Scand J Clin Lab Invest Suppl Date: 1968

Live Blastomyces dermatitidis yeast-induced responses of immune and nonimmune human mononuclear cells.

1. Variation in lymphocyte reactivity to histoplasmin during the course of chronic pulmonary histoplasmosis.

2. Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

3. Histologic reactions to cell walls of an avirulent and a virulent strain of Blastomyces dermatitidis.

4. State of the art: histoplasmosis.

5. Immunologic studies of patients with histoplasmosis.

6. Cell-mediated immune responses in sporotrichosis.

7. Human lymphocyte blastogenesis induced by living and dead Histoplasma capsulatum yeasts and soluble yeast autolysate.

8. Immunomodulation by Blastomyces dermatitidis: functional activity of murine peritoneal macrophages.

9. INTRACELLULAR BEHAVIOR OF HISTOPLASMA CAPSULATUM.

10. Blastomyces dermatitidis antigen-induced lymphocytes reactivity in human blastomycosis.

Review 1. Host-parasite interaction in fungal infections.

2. The unappreciated intracellular lifestyle of Blastomyces dermatitidis.