Literature DB >> 6512242

Situs inversus in homozygous mice without immotile cilia.

M A Handel, J R Kennedy.   

Abstract

Mice homozygous for the mutation situs inversus, iv, are characterized by situs inversus in 50 percent of the individuals. We have investigated the ultrastructure and motility of tracheal cilia and sperm tails in homozygous individuals with and without situs inversus. We found no abnormalities of ciliary structure. Therefore, ciliary immotility is not an essential correlate of situs inversus.

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Year:  1984        PMID： 6512242     DOI： 10.1093/oxfordjournals.jhered.a109995

Source DB:  PubMed          Journal:  J Hered        ISSN： 0022-1503            Impact factor:   2.645


  7 in total

1.  Characterization of a novel human dynein-related gene that is specifically expressed in testis.

Authors:  I Milisav; M H Jones; N A Affara
Journal:  Mamm Genome       Date:  1996-09       Impact factor: 2.957

2.  A potential human axonemal dynein heavy-chain gene maps to 17q25.

Authors:  I Milisav; N A Affara
Journal:  Mamm Genome       Date:  1998-05       Impact factor: 2.957

3.  Actin bundles on the right side in the caudal part of the heart tube play a role in dextro-looping in the embryonic chick heart.

Authors:  N Itasaki; H Nakamura; H Sumida; M Yasuda
Journal:  Anat Embryol (Berl)       Date:  1991

4.  Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetry.

Authors:  J Chen; H J Knowles; J L Hebert; B P Hackett
Journal:  J Clin Invest       Date:  1998-09-15       Impact factor: 14.808

5.  Linkage mapping of a mouse gene, iv, that controls left-right asymmetry of the heart and viscera.

Authors:  M Brueckner; P D'Eustachio; A L Horwich
Journal:  Proc Natl Acad Sci U S A       Date:  1989-07       Impact factor: 11.205

6.  Targeted deletion of the ATP binding domain of left-right dynein confirms its role in specifying development of left-right asymmetries.

Authors:  D M Supp; M Brueckner; M R Kuehn; D P Witte; L A Lowe; J McGrath; J Corrales; S S Potter
Journal:  Development       Date:  1999-12       Impact factor: 6.868

7.  A novel hypomorphic allele of Spag17 causes primary ciliary dyskinesia phenotypes in mice.

Authors:  Zakia Abdelhamed; Marshall Lukacs; Sandra Cindric; Saima Ali; Heymut Omran; Rolf W Stottmann
Journal:  Dis Model Mech       Date:  2020-10-30       Impact factor: 5.758
  7 in total

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