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Literature DB >> 6511883

Rapid determination of 5-fluorocytosine levels in blood.

M A Noble, B Harper, A G Grant, M Bernstein.

Abstract

Levels of 5-fluorocytosine in blood were rapidly calculated by determining the amount of competition in the creatinine iminohydrolase (creatinine deiminase; EC 3.5.4.21) assay for creatinine with the Kodak Ektachem system (Eastman Kodak Co., Rochester, N.Y.). The correlation with bioassay values was extremely high (r = 0.982). Standards and samples were highly stable over time.

Entities: Chemical

Mesh：

Substances：

Year: 1984 PMID： 6511883 PMCID： PMC271494 DOI： 10.1128/jcm.20.5.996-997.1984

Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948

8 in total

1. Fluorometric measurement of 5-fluorocytosine in biological fluids.

Authors: D Wade; G Sudlow
Journal: J Pharm Sci Date: 1973-05 Impact factor: 3.534

2. Creatinine assay by a reaction-kinetic principle.

Authors: K Larsen
Journal: Clin Chim Acta Date: 1972-10 Impact factor: 3.786

3. Rapid, simple bioassay for 5-fluorocytosine in the presence of amphotericin B.

Authors: R L Kaspar; D J Drutz
Journal: Antimicrob Agents Chemother Date: 1975-04 Impact factor: 5.191

Review 4. Strategies in the treatment of systemic fungal infections.

Authors: G Medoff; G S Kobayashi
Journal: N Engl J Med Date: 1980-01-17 Impact factor: 91.245

5. High performance liquid chromatographic (HPLC) and other non-biological methods for quantitation of antifungal drugs.

Authors: D W Warnock; M D Richardson; A Turner
Journal: J Antimicrob Chemother Date: 1982-12 Impact factor: 5.790

6. Evidence for conversion of 5-fluorocytosine to 5-fluorouracil in humans: possible factor in 5-fluorocytosine clinical toxicity.

Authors: R B Diasio; D E Lakings; J E Bennett
Journal: Antimicrob Agents Chemother Date: 1978-12 Impact factor: 5.191

7. Pharmacological studies with 5-fluorocytosine.

Authors: E R Block; J E Bennett
Journal: Antimicrob Agents Chemother Date: 1972-06 Impact factor: 5.191

8. Bone marrow toxicity associated with 5-fluorocytosine therapy.

Authors: C A Kauffman; P T Frame
Journal: Antimicrob Agents Chemother Date: 1977-02 Impact factor: 5.191

8 in total

4 in total

1. Performance characteristics of two bioassays and high-performance liquid chromatography for determination of flucytosine in serum.

Authors: G St-Germain; S Lapierre; D Tessier
Journal: Antimicrob Agents Chemother Date: 1989-08 Impact factor: 5.191