Literature DB >> 6510717

Complete nucleotide sequence of hepatitis B virus DNA of subtype adr and its conserved gene organization.

M Kobayashi, K Koike.   

Abstract

The complete nucleotide sequence of hepatitis B virus (HBV) DNA from Dane particles of subtype adr was determined. The 3215-bp sequence showed the presence of genes for the surface antigen (226 amino acids) and core antigen (183 amino acids), in addition to two (long and small) open reading frames (ORFs) capable of coding the 843 and 154 amino acids. These ORFs differed from those of the other adr clones so far reported [Ono et al., Nucl. Acids Res. 11 (1983) 1747-1757; Fujiyama et al., Nucl. Acids Res. 11 (1983) 4601-4610]. The gene organization of HBV DNA was found to be well conserved irrespective of subtype. The direct repeat of the undecanucleotide sequence near the 5' ends of the short (S) and long (L) strands of HBV DNA and the two small direct repeats between both 5' ends were found to be characteristic structures.

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Year:  1984        PMID： 6510717     DOI： 10.1016/0378-1119(84)90124-0

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  58 in total

1.  A frequent, naturally occurring mutation (P130T) of human hepatitis B virus core antigen is compensatory for immature secretion phenotype of another frequent variant (I97L).

Authors:  T T Yuan; C Shih
Journal:  J Virol       Date:  2000-05       Impact factor: 5.103

2.  Subtype-independent immature secretion and subtype-dependent replication deficiency of a highly frequent, naturally occurring mutation of human hepatitis B virus core antigen.

Authors:  T T Yuan; P C Tai; C Shih
Journal:  J Virol       Date:  1999-12       Impact factor: 5.103

3.  Replication advantage and host factor-independent phenotypes attributable to a common naturally occurring capsid mutation (I97L) in human hepatitis B virus.

Authors:  Fat-Moon Suk; Min-Hui Lin; Margaret Newman; Shann Pan; Sheng-Hsuan Chen; Jean-Dean Liu; Chiaho Shih
Journal:  J Virol       Date:  2002-12       Impact factor: 5.103

4.  The complete nucleotide sequence of hepatitis B virus, subtype adr (SRADR) and phylogenetic analysis.

Authors:  M Mukaide; T Kumazawa; A Hoshi; R Kawaguchi; K Hikiji
Journal:  Nucleic Acids Res       Date:  1992-11-25       Impact factor: 16.971

5.  Differential formation of disulfide linkages in the core antigen of extracellular and intracellular hepatitis B virus core particles.

Authors:  K S Jeng; C P Hu; C M Chang
Journal:  J Virol       Date:  1991-07       Impact factor: 5.103

6.  Tight clustering of human hepatitis B virus integration sites in hepatomas near a triple-stranded region.

Authors:  C Shih; K Burke; M J Chou; J B Zeldis; C S Yang; C S Lee; K J Isselbacher; J R Wands; H M Goodman
Journal:  J Virol       Date:  1987-11       Impact factor: 5.103

7.  Subgenomic studies on hepatitis B virus DNA integrated into the genome of hepatocellular carcinoma.

Authors:  K Togawa; T Arima; H Nagashima
Journal:  Gastroenterol Jpn       Date:  1987-10

8.  Transcriptional trans-activating function of hepatitis B virus.

Authors:  J S Twu; R H Schloemer
Journal:  J Virol       Date:  1987-11       Impact factor: 5.103

9.  Association between frequency of amino acid changes in core region of hepatitis B virus (HBV) and the presence of precore mutation in Japanese HBV carriers.

Authors:  T Karasawa; T Shirasawa; Y Okawa; A Kuramoto; N Shimada; Y Aizawa; M Zeniya; G Toda
Journal:  J Gastroenterol       Date:  1997-10       Impact factor: 7.527

10.  Enhanced replication of a hepatitis B virus mutant associated with an epidemic of fulminant hepatitis.

Authors:  K Hasegawa; J Huang; S A Rogers; H E Blum; T J Liang
Journal:  J Virol       Date:  1994-03       Impact factor: 5.103
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