Literature DB >> 6509321

The colchicine experimental epileptic focus: an intracellular study.

A F Reynolds, J C Oakley.   

Abstract

A new experimental epileptic focus is described in which colchicine is topically applied to neocortex. Stable epileptiform discharges developed, with bursts of action potentials, coincident with the surface epileptiform events. There were depolarizing and hyperpolarizing neuronal potentials and glial depolarizations concomitantly with the surface epileptic spikes.

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Year:  1984        PMID: 6509321     DOI: 10.1016/0006-8993(84)90126-4

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  1 in total

1.  Epileptic seizure after treatment with thiocolchicoside.

Authors:  Pedro Giavina-Bianchi; Mara Giavina-Bianchi; Luciana Kase Tanno; Luis Felipe Chiaverini Ensina; Antôno Abílio Motta; Jorge Kalil
Journal:  Ther Clin Risk Manag       Date:  2009-08-20       Impact factor: 2.423

  1 in total

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