| Literature DB >> 6508988 |
M Horowitz, D J Hetzel, P J Buckle, B E Chatterton, D J Shearman.
Abstract
The effect of a single oral dose of omeprazole (90 mg) on gastric emptying was assessed with a dual isotope scintigraphic technique in eight patients with a history of duodenal ulcer disease. Omeprazole had no significant effect on solid or liquid gastric emptying. The bioavailability (AUC0-2 h) of omeprazole in all patients was greater than that required for total suppression of acid secretion. No adverse clinical or laboratory effects were observed.Entities:
Mesh：
Substances：
Year: 1984 PMID： 6508988 PMCID： PMC1463542 DOI： 10.1111/j.1365-2125.1984.tb02544.x
Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335