Literature DB >> 6508777

A new purification procedure for Clostridium difficile enterotoxin.

B Rihn, J M Scheftel, R Girardot, H Monteil.   

Abstract

Clostridium difficile produces two toxins, an enterotoxin and a cytotoxin. The enterotoxin was purified using fast methods (tangential flow filtration, fast protein liquid chromatography). The purified enterotoxin is composed of two subunits (A1 = 41,500, A2 = 16,000) and its pI is 3.5.

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Year:  1984        PMID： 6508777     DOI： 10.1016/0006-291x(84)91013-1

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  10 in total

1.  Comparative sequence analysis of the Clostridium difficile toxins A and B.

Authors:  C von Eichel-Streiber; R Laufenberg-Feldmann; S Sartingen; J Schulze; M Sauerborn
Journal:  Mol Gen Genet       Date:  1992-05

2.  Molecular characterization of the Clostridium difficile toxin A gene.

Authors:  C H Dove; S Z Wang; S B Price; C J Phelps; D M Lyerly; T D Wilkins; J L Johnson
Journal:  Infect Immun       Date:  1990-02       Impact factor: 3.441

3.  Analysis of latex agglutination test for Clostridium difficile toxin A (D-1) and differentiation between C difficile toxins A and B and latex reactive protein.

Authors:  S P Borriello; F E Barclay; P J Reed; A R Welch; J D Brown; D W Burdon
Journal:  J Clin Pathol       Date:  1987-05       Impact factor: 3.411

4.  Characterization of toxins A and B of Clostridium difficile with monoclonal antibodies.

Authors:  D M Lyerly; C J Phelps; J Toth; T D Wilkins
Journal:  Infect Immun       Date:  1986-10       Impact factor: 3.441

5.  Identification of toxigenic Clostridium difficile strains by using a toxin A gene-specific probe.

Authors:  B W Wren; C L Clayton; N B Castledine; S Tabaqchali
Journal:  J Clin Microbiol       Date:  1990-08       Impact factor: 5.948

6.  Effect of toxin A and B of Clostridium difficile on rabbit ileum and colon.

Authors:  T J Mitchell; J M Ketley; S C Haslam; J Stephen; D W Burdon; D C Candy; R Daniel
Journal:  Gut       Date:  1986-01       Impact factor: 23.059

7.  Incidence and significance of Clostridium difficile in hospitalized cancer patients.

Authors:  M Gérard; N Defresne; D Daneau; P Van der Auwera; M Delmée; A M Bourguignon; F Meunier
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1988-04       Impact factor: 3.267

Review 8.  Clostridium difficile: its disease and toxins.

Authors:  D M Lyerly; H C Krivan; T D Wilkins
Journal:  Clin Microbiol Rev       Date:  1988-01       Impact factor: 26.132

9.  Purification of Clostridium difficile toxin A by affinity chromatography on immobilized thyroglobulin.

Authors:  H C Krivan; T D Wilkins
Journal:  Infect Immun       Date:  1987-08       Impact factor: 3.441

Review 10.  Clostridium difficile: clinical disease and diagnosis.

Authors:  F C Knoop; M Owens; I C Crocker
Journal:  Clin Microbiol Rev       Date:  1993-07       Impact factor: 26.132
  10 in total

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