Literature DB >> 6508748

Effect of inositol and tri-iodothyronine on the hormonal responsiveness of hepatocytes obtained from partially hepatectomized rats.

J Huerta-Bahena, J A García-Sáinz.   

Abstract

Hepatocytes obtained from animals partially hepatectomized (72 h before the experiment) have a diminished responsiveness to alpha 1-adrenergic amines, vasopressin, angiotensin and glucagon and an increased responsiveness to beta-adrenergic amines. Administration of inositol or tri-iodothyronine to the hepatectomized animals induced a recovery in the hepatocyte responsiveness to the Ca2+-dependent hormones and abolished that to beta-adrenergic amines; the response to glucagon was not improved.

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Year:  1984        PMID： 6508748      PMCID： PMC1144381          DOI： 10.1042/bj2230925

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  14 in total

Review 1.  Inositol phospholipids and cell surface receptor function.

Authors:  R H Michell
Journal:  Biochim Biophys Acta       Date:  1975-03-25

Review 2.  Inositol trisphosphate and diacylglycerol as second messengers.

Authors:  M J Berridge
Journal:  Biochem J       Date:  1984-06-01       Impact factor: 3.857

3.  Stimulation by vasopressin and alpha-catecholamines of phosphatidylinositol formation in isolated rat liver parenchymal cells.

Authors:  M E Tolbert; A C White; K Aspry; J Cutts; J N Fain
Journal:  J Biol Chem       Date:  1980-03-10       Impact factor: 5.157

Review 4.  Role of phosphatidylinositol turnover in alpha 1 and of adenylate cyclase inhibition in alpha 2 effects of catecholamines.

Authors:  J N Fain; J A García-Sáinz
Journal:  Life Sci       Date:  1980-04-14       Impact factor: 5.037

5.  Adrenergic regulation of glycogenolysis in rat liver after cholestasis. Modulation of the balance between alpha 1 and beta 2 receptors.

Authors:  M Aggerbeck; N Ferry; E S Zafrani; M C Billon; R Barouki; J Hanoune
Journal:  J Clin Invest       Date:  1983-03       Impact factor: 14.808

6.  Roles of alpha 1- and beta-adrenergic receptors in adrenergic responsiveness of liver cells formed after partial hepatectomy.

Authors:  J Huerta-Bahena; R Villalobos-Molina; J A García-Saínz
Journal:  Biochim Biophys Acta       Date:  1983-09-22

7.  Selective hormonal control of myo-inositol biosynthesis in reproductive organs and liver of the male rat.

Authors:  R Hasegawa; F Eisenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1981-08       Impact factor: 11.205

8.  Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones.

Authors:  J A Creba; C P Downes; P T Hawkins; G Brewster; R H Michell; C J Kirk
Journal:  Biochem J       Date:  1983-06-15       Impact factor: 3.857

9.  Regulation of hepatic regeneration in rats by synergistic action of insulin and glucagon.

Authors:  M L Bucher; M N Swaffield
Journal:  Proc Natl Acad Sci U S A       Date:  1975-03       Impact factor: 11.205

10.  High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study.

Authors:  M N Berry; D S Friend
Journal:  J Cell Biol       Date:  1969-12       Impact factor: 10.539
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