| Literature DB >> 650698 |
D L Bronson, D M Ritzi, E E Fraley, A J Dalton.
Abstract
Ultrastructural examination of primary and subcultured epithelial cells established in vitro from an abdominal metastasis of a human testicular tumor revealed particles with the morphology of retroviruses. These structures, found only after extensive scanning of the cells, were observed budding from microvilli and from the outer cell membrane and as extracellular particles. Production of these virus particles was stimulated by the incubation of cells in culture medium containing 5-iodo-2'-deoxyuridine and dexamethasone.Entities:
Mesh:
Substances:
Year: 1978 PMID: 650698 DOI: 10.1093/jnci/60.6.1305
Source DB: PubMed Journal: J Natl Cancer Inst ISSN: 0027-8874 Impact factor: 13.506