Literature DB >> 6505700

Smell identification ability: changes with age.

R L Doty, P Shaman, S L Applebaum, R Giberson, L Siksorski, L Rosenberg.   

Abstract

Smell identification ability was measured in 1955 persons ranging in age from 5 to 99 years. On the average, women outperformed men at all ages, and nonsmokers outperformed smokers. Peak performance occurred in the third through fifth decades and declined markedly after the seventh. More than half of those 65 to 80 years old evidenced major olfactory impairment. After 80 years, more than three-quarters evidenced major impairment. Given these findings, it is not surprising that many elderly persons complain that food lacks flavor and that the elderly account for a disproportionate number of accidental gas poisoning cases each year.

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Year:  1984        PMID: 6505700     DOI: 10.1126/science.6505700

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  250 in total

1.  Genetic and environmental influences on odor identification ability in the very old.

Authors:  Richard L Doty; Inge Petersen; Nii Mensah; Kaare Christensen
Journal:  Psychol Aging       Date:  2011-05-30

2.  Age-associated loss of selectivity in human olfactory sensory neurons.

Authors:  Nancy E Rawson; George Gomez; Beverly J Cowart; Andres Kriete; Edmund Pribitkin; Diego Restrepo
Journal:  Neurobiol Aging       Date:  2011-11-09       Impact factor: 4.673

3.  Both odor identification and ApoE-ε4 contribute to normative cognitive aging.

Authors:  Deborah Finkel; Chandra A Reynolds; Maria Larsson; Margaret Gatz; Nancy L Pedersen
Journal:  Psychol Aging       Date:  2011-04-25

4.  Age-related changes in p2 odorant receptor mapping in the olfactory bulb.

Authors:  Richard M Costanzo; Masayoshi Kobayashi
Journal:  Chem Senses       Date:  2010-03-15       Impact factor: 3.160

5.  Olfactory dysfunction and cardiovascular dysautonomia in Parkinson's disease.

Authors:  Hisayoshi Oka; Chizuko Toyoda; Makiko Yogo; Soichiro Mochio
Journal:  J Neurol       Date:  2010-01-30       Impact factor: 4.849

6.  Odor identification and mortality in old age.

Authors:  Robert S Wilson; Lei Yu; David A Bennett
Journal:  Chem Senses       Date:  2010-10-05       Impact factor: 3.160

Review 7.  Regulated reprogramming in the regeneration of sensory receptor cells.

Authors:  Olivia Bermingham-McDonogh; Thomas A Reh
Journal:  Neuron       Date:  2011-08-11       Impact factor: 17.173

Review 8.  Mechanisms of the anorexia of aging-a review.

Authors:  Adam Wysokiński; Tomasz Sobów; Iwona Kłoszewska; Tomasz Kostka
Journal:  Age (Dordr)       Date:  2015-08-01

9.  Episodic memory of odors stratifies Alzheimer biomarkers in normal elderly.

Authors:  Alefiya Dhilla Albers; Josephine Asafu-Adjei; Mary K Delaney; Kathleen E Kelly; Teresa Gomez-Isla; Deborah Blacker; Keith A Johnson; Reisa A Sperling; Bradley T Hyman; Rebecca A Betensky; Lloyd Hastings; Mark W Albers
Journal:  Ann Neurol       Date:  2016-11-23       Impact factor: 10.422

10.  Pathophysiology of Olfactory Disorders and Potential Treatment Strategies.

Authors:  Stefania Goncalves; Bradley J Goldstein
Journal:  Curr Otorhinolaryngol Rep       Date:  2016-06
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