Chemotherapy of bovine tropical theileriosis: Theileria annulata infection.

Seven groups of calves were treated with parvaquone (993C: Clexon, Wellcome) (20 mg kg-1 intramuscularly) or halofuginone lactate (1.2 mg kg-1 orally) on the first, third or sixth day of significant pyrexia following artificial infection with the Hissar strain of Theileria annulata. Eight untreated control animals developed severe theileriosis and five died. All animals treated with parvaquone or halofuginone lactate on the first or third day of fever underwent relatively mild theileriosis and all of them recovered. One of five animals treated with parvaquone and three of six treated with halofuginone on the sixth day of fever died of theileriosis.