Literature DB >> 6504875

[Autoimplantation of cryopreserved (- 196 degrees C) thyroid gland parenchyma as a treatment method in postoperative hypothyroidism].

N S Pushkar', V A Makedonskaia, A M Utevskiĭ, V A Chuĭko, L G Karpenko.   

Abstract

To treat postoperative hypothyrosis, use was made of implantation of autologous thyroid tissue preserved and stored for 4 to 12 months before patients developed hypothyrosis. It was established that the treatment was followed by an increase in 131I accumulation in the body at the expense of its accumulation by the implant and stimulation of the process in the stump. This was paralleled by a considerable rise in T3 and T4 and reduction in TTH in the patients' blood. The patients substantially improved while the manifestations of hypothyrosis disappeared. The effects detected could be seen throughout the whole observation period (up to 18 months). The patients did not require any additional drug treatment. The data provided attest to the efficacy of autoimplantation of cryopreserved thyroid parenchyma for the treatment of postoperative hypothyrosis.

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Mesh:

Year:  1984        PMID: 6504875

Source DB:  PubMed          Journal:  Probl Endokrinol (Mosk)        ISSN: 0375-9660


  3 in total

1.  Xenotransplantation of cultured newborn pig thyroid tissue for the treatment of post-radioiodine hypothyroidism in rats.

Authors:  I Pasteur; N Tronko; I Drozdovich; S Donich; L Voitenko
Journal:  Cytotechnology       Date:  2000-07       Impact factor: 2.058

Review 2.  Review of Heterotopic Thyroid Autotransplantation.

Authors:  Mahmoud Sakr; Ahmed Mahmoud
Journal:  Clin Exp Otorhinolaryngol       Date:  2017-05-24       Impact factor: 3.372

3.  Cryopreserved Rat Thyroid Autotransplantation in the Treatment of Postoperative Hypothyroidism.

Authors:  Marcel Vasconcellos; Amabile Maran Carra; Olavo Borges Franco; Wagner Baetas-da-Cruz; Manoel Luiz Ferreira; Paulo Cesar Silva; Sergio Augusto Lopes de Souza; Leandro Miranda-Alves; Denise Pires de Carvalho; Alberto Schanaider
Journal:  Front Endocrinol (Lausanne)       Date:  2021-05-17       Impact factor: 5.555

  3 in total

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